KEGG   DRUG: ArformoterolHelp
Entry
D07463                      Drug                                   

Name
Arformoterol (INN)
Formula
C19H24N2O4
Exact mass
344.1736
Mol weight
344.4049
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01455  beta-Adrenergic receptor agonist
   DG01452  beta2-Adrenergic receptor agonist
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
Remark
Chemical group: 
Activity
Antiasthmatic, Bronchodilator, beta2-Adrenergic receptor agonist
Comment
Phenethylamine derivative
Long-acting beta-adrenoceptor agonist (LABA)
Target
ADRB2 [HSA:154] [KO:K04142]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
Metabolism
Enzyme: UGT [KO:K00699]
Interaction
Drug interaction
Brite
USP drug classification [BR:br08302]
 Respiratory Tract/Pulmonary Agents
  Bronchodilators, Sympathomimetic
   Arformoterol
    D07463  Arformoterol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Arformoterol
      D07463  Arformoterol (INN)
BRITE hierarchy
Other DBs
CAS: 
67346-49-0
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        25
            1   C8y C    21.2100  -17.9900
            2   C8x C    19.9500  -18.6900
            3   C8x C    21.2100  -16.5900
            4   C1c C    22.4000  -18.6900
            5   C8y C    18.7600  -17.9900
            6   C8x C    19.9500  -15.8900
            7   C1b C    23.5900  -17.9900
            8   C8y C    18.7600  -16.5900
            9   N1b N    17.5700  -18.6900
            10  N1b N    24.7800  -18.6900
            11  O1a O    17.5700  -15.8900
            12  C4a C    16.3100  -17.9900
            13  C1c C    26.0400  -17.9900
            14  O4a O    15.1200  -18.6900
            15  C1b C    27.2300  -18.6900
            16  C8y C    28.4200  -17.9900
            17  C8x C    28.4200  -16.5900
            18  C8x C    29.6100  -18.6900
            19  C8x C    29.6100  -15.8900
            20  C8x C    30.8700  -17.9900
            21  C8y C    30.8700  -16.5900
            22  O2a O    32.0600  -15.8200
            23  C1a C    33.2500  -16.5200
            24  C1a C    26.0400  -16.5900
            25  O1a O    22.4000  -20.0900
BOND        26
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    8  11 1
            11    9  12 1
            12   10  13 1
            13   12  14 2
            14   13  15 1
            15   15  16 1
            16   16  17 2
            17   16  18 1
            18   17  19 1
            19   18  20 2
            20   19  21 2
            21   21  22 1
            22   22  23 1
            23    6   8 1
            24   20  21 1
            25   13  24 1 #Down
            26    4  25 1 #Down

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