KEGG   DRUG: D07477Help
Entry
D07477                      Drug                                   

Name
Atropine oxide (INN);
Apitropin (TN)
Formula
C17H23NO4
Exact mass
305.1627
Mol weight
305.3688
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antispasmodic
Remark
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BA Belladonna alkaloids, tertiary amines
     A03BA01 Atropine
      D07477  Atropine oxide (INN)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Atropine
    D07477  Atropine oxide (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Atropine
      D07477  Atropine oxide (INN)
BRITE hierarchy
Other DBs
CAS: 
4438-22-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1x C    18.9000  -18.7600
            2   C1x C    19.2500  -17.5700
            3   C1y C    20.0900  -18.4800
            4   C1y C    20.4400  -17.2900
            5   N2y N    19.1800  -15.9600
            6   C1x C    21.9800  -18.4800
            7   C1x C    21.7000  -17.2900
            8   C1y C    23.0300  -19.0400
            9   O7a O    24.0800  -19.8800
            10  C7a C    25.2700  -19.8800
            11  C1c C    25.9000  -18.8300
            12  O6a O    25.9000  -21.0700
            13  C8y C    27.1600  -18.8300
            14  C1b C    25.2700  -17.7800
            15  O1a O    25.9000  -16.7300
            16  C8x C    27.8600  -20.0900
            17  C8x C    29.2600  -20.0900
            18  C8x C    29.9600  -18.8300
            19  C8x C    29.2600  -17.6400
            20  C8x C    27.8600  -17.6400
            21  C1a C    18.4100  -14.7700
            22  O3a O    19.8800  -14.7476
BOND        24
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1 #Down
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1
            24    5  22 2

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