KEGG   DRUG: D07499Help
Entry
D07499                      Drug                                   

Name
Benazepril (INN);
Benazepril Sandoz (TN);
Forteekor [veterinary] (TN)
Formula
C24H28N2O5
Exact mass
424.1998
Mol weight
424.4895
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
ACE-inhibitor, Antihypertensive
Remark
Same as: 
ATC code: 
Drug group: 
Comment
prodrug, active substance: Benazeprilat [DR:D03077]
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA07 Benazepril
      D07499  Benazepril (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Angiotensin-converting Enzyme (ACE) Inhibitors
   Benazepril
    D07499  Benazepril (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE)
    Benazepril
     D07499  Benazepril (INN)
BRITE hierarchy
Other DBs
CAS: 
86541-75-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C1x C    20.1600  -19.3900
            2   C8y C    19.2500  -18.2700
            3   C8y C    19.5300  -16.9400
            4   N1y N    20.7900  -16.3100
            5   C1x C    21.5600  -19.3900
            6   C5x C    22.0500  -16.8700
            7   C1y C    22.4000  -18.2000
            8   C8x C    18.4800  -15.9600
            9   C8x C    17.1500  -16.4500
            10  C8x C    16.8700  -17.7800
            11  C8x C    17.9200  -18.6900
            12  C1b C    20.7200  -14.9100
            13  C6a C    21.9100  -14.1400
            14  O6a O    23.1700  -14.8400
            15  O6a O    21.9800  -12.8100
            16  O5x O    23.1700  -15.9600
            17  N1b N    23.8000  -18.2000
            18  C1c C    24.5000  -19.4600
            19  C1b C    25.9000  -19.4600
            20  C7a C    23.8000  -20.6500
            21  C1b C    26.6000  -18.2000
            22  C8y C    28.0000  -18.2000
            23  O6a O    22.4000  -20.6500
            24  O7a O    24.5000  -21.8400
            25  C1b C    25.9000  -21.8400
            26  C1a C    26.6000  -23.0300
            27  C8x C    28.7000  -19.4600
            28  C8x C    30.1000  -19.4600
            29  C8x C    30.8000  -18.2700
            30  C8x C    30.1000  -17.0100
            31  C8x C    28.7000  -17.0100
BOND        33
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    4  12 1
            14   12  13 1
            15   13  14 1
            16   13  15 2
            17    6  16 2
            18    7  17 1 #Up
            19   17  18 1
            20   18  19 1 #Up
            21   18  20 1
            22   19  21 1
            23   21  22 1
            24   20  23 2
            25   20  24 1
            26   24  25 1
            27   25  26 1
            28   22  27 2
            29   27  28 1
            30   28  29 2
            31   29  30 1
            32   30  31 2
            33   22  31 1

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