KEGG   DRUG: D07526Help
Entry
D07526                      Drug                                   

Name
Betaxolol (INN);
Betaxolol (TN)
Formula
C18H29NO3
Exact mass
307.2147
Mol weight
307.4278
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
beta1-Adrenergic blocking [DS:H00612]
Remark
Same as: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04540  Gap junction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB05 Betaxolol
      D07526  Betaxolol (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01ED Beta blocking agents
     S01ED02 Betaxolol
      D07526  Betaxolol (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Beta-adrenergic Blocking Agents
   Betaxolol
    D07526  Betaxolol (INN)
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Betaxolol
    D07526  Betaxolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Betaxolol
      D07526  Betaxolol (INN)
BRITE hierarchy
Other DBs
CAS: 
63659-18-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    24.7800  -18.2700
            2   C8x C    23.5900  -18.9700
            3   C8x C    24.7800  -16.8700
            4   O2a O    25.9700  -19.0400
            5   C8x C    22.3300  -18.2700
            6   C8x C    23.5900  -16.1700
            7   C1b C    27.1600  -18.3400
            8   C8y C    22.3300  -16.8700
            9   C1c C    28.4200  -19.0400
            10  C1b C    21.1400  -16.1700
            11  C1b C    29.6100  -18.3400
            12  O1a O    28.4200  -20.4400
            13  C1b C    19.9500  -16.8700
            14  N1b N    30.8000  -19.0400
            15  O2a O    18.6900  -16.1700
            16  C1c C    32.0600  -18.3400
            17  C1b C    17.5000  -16.8700
            18  C1a C    33.2500  -19.0400
            19  C1a C    32.0600  -16.9400
            20  C1y C    16.3100  -16.1700
            21  C1x C    15.0500  -16.8000
            22  C1x C    15.1200  -15.4000
BOND        23
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14   13  15 1
            15   14  16 1
            16   15  17 1
            17   16  18 1
            18   16  19 1
            19   17  20 1
            20   20  21 1
            21   20  22 1
            22    6   8 2
            23   21  22 1

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