KEGG   DRUG: D07526Help
Entry
D07526                      Drug                                   

Name
Betaxolol (INN);
Betaxolol (TN)
Formula
C18H29NO3
Exact mass
307.2147
Mol weight
307.4278
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
beta1-Adrenergic blocking [DS:H00612]
Remark
Same as: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04540  Gap junction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB05 Betaxolol
      D07526  Betaxolol (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01ED Beta blocking agents
     S01ED02 Betaxolol
      D07526  Betaxolol (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Beta-adrenergic Blocking Agents
   Betaxolol
    D07526  Betaxolol (INN)
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Betaxolol
    D07526  Betaxolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Betaxolol
      D07526  Betaxolol (INN)
BRITE hierarchy
Other DBs
CAS: 
63659-18-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   O2a O    20.5100  -14.6300
            2   C1b C    21.7000  -13.9300
            3   C1c C    22.9600  -14.6300
            4   C1b C    24.1500  -13.9300
            5   O1a O    22.9600  -16.0300
            6   N1b N    25.3400  -14.6300
            7   C1c C    26.6000  -13.9300
            8   C1a C    27.7900  -14.6300
            9   C1a C    26.6000  -12.5300
            10  C8y C    20.5100  -16.0300
            11  C8x C    19.3200  -16.7300
            12  C8x C    19.3200  -18.1300
            13  C8y C    20.5100  -18.8300
            14  C8x C    21.7000  -18.1300
            15  C8x C    21.7000  -16.7300
            16  C1b C    20.5100  -20.2300
            17  C1b C    19.3200  -21.0000
            18  O2a O    18.1300  -20.3000
            19  C1b C    16.9400  -21.0000
            20  C1y C    15.6800  -20.3700
            21  C1x C    14.2800  -20.3700
            22  C1x C    14.9800  -19.1800
BOND        23
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     3   5 1
            5     4   6 1
            6     6   7 1
            7     7   8 1
            8     7   9 1
            9     1  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   13  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   21  20 1
            22   22  21 1
            23   22  20 1

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