KEGG   DRUG: D07543Help
Entry
D07543                      Drug                                   

Name
Brompheniramine (INN);
Brotane (TN)
Formula
C16H19BrN2
Exact mass
318.0732
Mol weight
319.2395
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
Same as: 
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB01 Brompheniramine
      D07543  Brompheniramine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Brompheniramine
      D07543  Brompheniramine (INN)
BRITE hierarchy
Other DBs
CAS: 
86-22-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C1c C    24.7800  -18.6900
            2   C8y C    23.5200  -19.3900
            3   C8y C    25.9700  -19.3900
            4   C1b C    24.7800  -17.2900
            5   C8x C    22.3300  -18.6900
            6   C8x C    23.5200  -20.7900
            7   C8x C    25.9700  -20.7900
            8   N5x N    27.1600  -18.6200
            9   C1b C    25.9700  -16.5900
            10  C8x C    21.1400  -19.3900
            11  C8x C    22.3300  -21.4900
            12  C8x C    27.1600  -21.4900
            13  C8x C    28.4200  -19.3900
            14  N1c N    25.9700  -15.1900
            15  C8y C    21.1400  -20.7900
            16  C8x C    28.4200  -20.7900
            17  C1a C    24.7100  -14.4900
            18  C1a C    27.1600  -14.4200
            19  X   Br   19.9500  -21.4900
BOND        20
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     5  10 2
            10    6  11 1
            11    7  12 2
            12    8  13 1
            13    9  14 1
            14   10  15 1
            15   12  16 1
            16   14  17 1
            17   14  18 1
            18   15  19 1
            19   11  15 2
            20   13  16 2

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