KEGG   DRUG: D07550Help
Entry
D07550                      Drug                                   

Name
Bunazosin (INN)
Formula
C19H27N5O3
Exact mass
373.2114
Mol weight
373.4494
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
alfa-Adrenergic blocking
Remark
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
Antiglaucoma agents
alpha-Adrenergic receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Bunazosin
      D07550  Bunazosin (INN)
BRITE hierarchy
Other DBs
CAS: 
80755-51-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C8y C    29.2600  -18.8300
            2   C8y C    29.2600  -20.2300
            3   C8x C    28.0000  -20.9300
            4   C8x C    28.0000  -18.1300
            5   C8y C    26.8100  -18.8300
            6   C8y C    26.8100  -20.2300
            7   C8y C    25.6200  -20.9300
            8   N5x N    24.3600  -20.2300
            9   C8y C    24.3600  -18.8300
            10  N5x N    25.6200  -18.1300
            11  N1y N    23.1700  -18.1300
            12  C1x C    23.1700  -16.7300
            13  C1x C    22.1900  -15.8200
            14  C1x C    21.9800  -18.9700
            15  N1y N    20.8600  -16.0300
            16  C1x C    20.6500  -18.5500
            17  C1x C    20.1600  -17.2200
            18  C5a C    20.1600  -14.7700
            19  C1b C    18.7600  -14.7700
            20  C1b C    18.0600  -13.5800
            21  C1a C    16.6600  -13.5800
            22  O5a O    20.8600  -13.5800
            23  O2a O    30.4500  -18.1300
            24  C1a C    31.6400  -18.8300
            25  O2a O    30.4500  -20.9300
            26  C1a C    31.6400  -20.2300
            27  N1a N    25.6200  -22.3300
BOND        29
            1    12  13 1
            2     1   2 2
            3    11  14 1
            4     2   3 1
            5    13  15 1
            6     3   6 2
            7    14  16 1
            8     5   4 2
            9    15  17 1
            10   16  17 1
            11    5   6 1
            12   15  18 1
            13    6   7 1
            14   18  19 1
            15    7   8 2
            16   19  20 1
            17    8   9 1
            18   20  21 1
            19    9  10 2
            20   18  22 2
            21   10   5 1
            22    1  23 1
            23    4   1 1
            24   23  24 1
            25    9  11 1
            26    2  25 1
            27   25  26 1
            28   11  12 1
            29    7  27 1

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