KEGG   DRUG: D07580Help
Entry
D07580                      Drug                                   

Name
Aspirin DL-lysine (JAN);
Aspirin lysine salt;
Aspegic (TN)
Formula
C9H7O4. C6H15N2O2
Exact mass
326.1478
Mol weight
326.345
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Analgesic;
Anticoagulant, platelet aggregation inhibitor;
Antiinflammatory;
Antipyretic
Remark
Comment
nonsteroidal antiinflammatory drug (NSAIDs)
Target
cyclooxygenase-1 (COX-1) inhibitor [HSA:5742] [KO:K00509];
cyclooxygenase-2 (COX-2) inhibitor [HSA:5743] [KO:K11987]
  Pathway
hsa00590  Arachidonic acid metabolism  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AD Other agents for local oral treatment
     A01AD05 Acetylsalicylic acid
      D07580  Aspirin DL-lysine (JAN)
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC06 Acetylsalicylic acid
      D07580  Aspirin DL-lysine (JAN)
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BA Salicylic acid and derivatives
     N02BA01 Acetylsalicylic acid
      D07580  Aspirin DL-lysine (JAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   cyclooxygenase-1 (COX-1) [HSA:5742] [KO:K00509]
    Acetylsalicylic acid [ATC:A01AD05 B01AC06 N02BA01]
     D07580  Aspirin lysine salt
   cyclooxygenase-2 (COX-2) [HSA:5743] [KO:K11987]
    Acetylsalicylic acid [ATC:A01AD05 B01AC06 N02BA01]
     D07580  Aspirin lysine salt
BRITE hierarchy
Other DBs
CAS: 
62952-06-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C8y C     9.2400  -18.1300
            2   C8y C    10.5000  -18.8300
            3   C8x C     8.0500  -18.8300
            4   C6a C     9.2400  -16.8700
            5   C8x C    10.5000  -20.2300
            6   O7a O    11.6200  -18.0600
            7   C8x C     8.0500  -20.2300
            8   O6a O    10.5000  -16.1700 #-
            9   O6a O     8.0500  -16.1700
            10  C8x C     9.2400  -20.9300
            11  C7a C    12.8800  -18.7600
            12  C1a C    14.0700  -18.0600
            13  O6a O    12.8800  -20.2300
            14  N1a N    25.9700  -17.6400 #+
            15  C1b C    24.7800  -18.3400
            16  C1b C    23.5900  -17.6400
            17  C1b C    22.3300  -18.3400
            18  C1b C    21.1400  -17.6400
            19  C1c C    19.9500  -18.3400
            20  C6a C    18.6900  -17.6400
            21  O6a O    17.5000  -18.3400
            22  O6a O    18.6900  -16.2400
            23  N1a N    19.9500  -19.7400
BOND        22
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11   11  12 1
            12   11  13 2
            13    7  10 2
            14   14  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   20  22 2
            22   19  23 1

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