| Entry |
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| Name |
Bupranolol (INN)
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| Formula |
C14H22ClNO2
|
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| Exact mass |
271.1339
|
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| Mol weight |
271.783
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| Structure |
     |
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| Activity |
Glaucoma treatment;
beta-Adrenergic blocking
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| Remark |
|
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| Target |
beta1-adrenergic receptor antagonist [HSA: 153] [KO: K04141]; beta2-adrenergic receptor antagonist [HSA: 154] [KO: K04142]; beta3-adrenergic receptor antagonist [HSA: 155] [KO: K04143] |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AA Beta blocking agents, non-selective
C07AA19 Bupranolol
D07590 Bupranolol (INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
beta1-adrenergic receptor [HSA:153] [KO:K04141]
Bupranolol [ATC:C07AA19]
D07590 Bupranolol (INN)
beta2-adrenergic receptor [HSA:154] [KO:K04142]
Bupranolol [ATC:C07AA19]
D07590 Bupranolol (INN)
beta3-adrenergic receptor [HSA:155] [KO:K04143]
Bupranolol [ATC:C07AA19]
D07590 Bupranolol (INN)
 |
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| Other DBs |
CAS: 14556-46-8 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 18
1 C8x C 21.0914 -17.1938
2 C8y C 21.0914 -18.6555
3 C8y C 19.8385 -16.4977
4 O2a O 22.3443 -19.3516
5 C8y C 19.8385 -19.3516
6 C8x C 18.6552 -17.1938
7 C1b C 23.4581 -18.6555
8 C8x C 18.6552 -18.6555
9 C1c C 24.7110 -19.3516
10 C1b C 25.9639 -18.6555
11 O1a O 24.7110 -20.7438
12 N1b N 27.1472 -19.3516
13 C1d C 28.4002 -18.6555
14 X Cl 19.8385 -20.7438
15 C1a C 19.8385 -15.1752
16 C1a C 29.5835 -19.3516
17 C1a C 28.4002 -17.2634
18 C1a C 29.5835 -17.9595
BOND 18
1 1 2 1
2 1 3 2
3 2 4 1
4 2 5 2
5 3 6 1
6 4 7 1
7 5 8 1
8 7 9 1
9 9 10 1
10 9 11 1
11 10 12 1
12 12 13 1
13 6 8 2
14 5 14 1
15 3 15 1
16 13 16 1
17 13 17 1
18 13 18 1
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