KEGG   DRUG: D07590Help
Entry
D07590                      Drug                                   

Name
Bupranolol (INN)
Formula
C14H22ClNO2
Exact mass
271.1339
Mol weight
271.783
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Glaucoma treatment;
beta-Adrenergic blocking
Remark
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA19 Bupranolol
      D07590  Bupranolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Bupranolol
      D07590  Bupranolol (INN)
    beta2-adrenergic receptor
     Bupranolol
      D07590  Bupranolol (INN)
    beta3-adrenergic receptor
     Bupranolol
      D07590  Bupranolol (INN)
BRITE hierarchy
Other DBs
CAS: 
14556-46-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8x C    21.0914  -17.1938
            2   C8y C    21.0914  -18.6555
            3   C8y C    19.8385  -16.4977
            4   O2a O    22.3443  -19.3516
            5   C8y C    19.8385  -19.3516
            6   C8x C    18.6552  -17.1938
            7   C1b C    23.4581  -18.6555
            8   C8x C    18.6552  -18.6555
            9   C1c C    24.7110  -19.3516
            10  C1b C    25.9639  -18.6555
            11  O1a O    24.7110  -20.7438
            12  N1b N    27.1472  -19.3516
            13  C1d C    28.4002  -18.6555
            14  X   Cl   19.8385  -20.7438
            15  C1a C    19.8385  -15.1752
            16  C1a C    29.5835  -19.3516
            17  C1a C    28.4002  -17.2634
            18  C1a C    29.5835  -17.9595
BOND        18
            1     1   2 1
            2     1   3 2
            3     2   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     9  10 1
            10    9  11 1
            11   10  12 1
            12   12  13 1
            13    6   8 2
            14    5  14 1
            15    3  15 1
            16   13  16 1
            17   13  17 1
            18   13  18 1

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