KEGG   DRUG: D07608Help
Entry
D07608                      Drug                                   

Name
Carazolol (INN);
Conducton (TN);
Suacron [veterinary] (TN)
Formula
C18H22N2O2
Exact mass
298.1681
Mol weight
298.3795
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
beta-Adrenergic blocking
Remark
Drug group: 
Target
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Carazolol
      D07608  Carazolol (INN)
BRITE hierarchy
Other DBs
CAS: 
57775-29-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1b C    20.9300  -15.4700
            2   C1c C    22.1900  -16.1700
            3   C1b C    23.3800  -15.4700
            4   N1b N    24.5700  -16.1700
            5   C1c C    25.8300  -15.4700
            6   C1a C    27.0200  -16.1700
            7   O1a O    22.1900  -17.5700
            8   C1a C    25.8300  -14.0700
            9   O2a O    19.7293  -16.1899
            10  C8y C    19.7293  -17.5899
            11  C8y C    18.5335  -18.2801
            12  C8y C    18.5333  -19.6801
            13  C8x C    19.7457  -20.3803
            14  C8x C    20.9415  -19.6901
            15  C8x C    20.9416  -18.2901
            16  C8y C    17.2020  -17.8473
            17  C8y C    16.3790  -18.9799
            18  N4x N    17.2018  -20.1126
            19  C8x C    16.6328  -16.5683
            20  C8x C    15.2404  -16.4218
            21  C8x C    14.4174  -17.5543
            22  C8x C    14.9867  -18.8334
BOND        24
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     2   7 1
            7     5   8 1
            8     1   9 1
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   11  16 1
            17   16  17 1
            18   17  18 1
            19   12  18 1
            20   16  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   17  22 2

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