KEGG   DRUG: CarteololHelp
Entry
D07624                      Drug                                   

Name
Carteolol (INN)
Formula
C16H24N2O3
Exact mass
292.1787
Mol weight
292.3734
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Cyp substrate
 DG01644  CYP2D6 substrate
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antiglaucoma, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142];
ADRB3 [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Gap junction
Salivary secretion
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA15 Carteolol
      D07624  Carteolol (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01ED Beta blocking agents
     S01ED05 Carteolol
      D07624  Carteolol (INN)
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Carteolol
    D07624  Carteolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Carteolol
      D07624  Carteolol (INN)
    beta2-adrenergic receptor
     Carteolol
      D07624  Carteolol (INN)
    beta3-adrenergic receptor
     Carteolol
      D07624  Carteolol (INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP2D6
   Carteolol
    D07624  Carteolol (INN)
BRITE hierarchy
Other DBs
CAS: 
51781-06-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C1x C    19.3200  -18.8300
            2   C5x C    19.3200  -20.2300
            3   N1x N    20.5800  -21.0000
            4   C8y C    21.7700  -20.2300
            5   C8y C    21.7700  -18.8300
            6   C1x C    20.5800  -18.1300
            7   C8x C    23.0300  -21.0000
            8   C8x C    24.2200  -20.2300
            9   C8x C    24.2200  -18.8300
            10  C8y C    23.0300  -18.1300
            11  O5x O    18.1300  -21.0000
            12  O2a O    23.0300  -16.7300
            13  C1b C    24.2200  -16.0300
            14  C1c C    25.4100  -16.7300
            15  C1b C    26.6000  -16.0300
            16  O1a O    25.4100  -18.1300
            17  N1b N    27.7900  -16.7300
            18  C1d C    28.9800  -16.0300
            19  C1a C    30.1700  -15.3300
            20  C1a C    29.6800  -17.2900
            21  C1a C    28.2800  -14.8400
BOND        22
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 2
            12    2  11 2
            13   10  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   14  16 1
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   18  20 1
            22   18  21 1

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