KEGG   DRUG: D07624Help
Entry
D07624                      Drug                                   

Name
Carteolol (INN)
Formula
C16H24N2O3
Exact mass
292.1787
Mol weight
292.3734
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Glaucoma treatment;
beta-Adrenergic blocking [DS:H00612]
Remark
Same as: 
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04540  Gap junction
hsa04970  Salivary secretion  
 
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA15 Carteolol
      D07624  Carteolol (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01ED Beta blocking agents
     S01ED05 Carteolol
      D07624  Carteolol (INN)
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Carteolol
    D07624  Carteolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Carteolol
      D07624  Carteolol (INN)
    beta2-adrenergic receptor
     Carteolol
      D07624  Carteolol (INN)
    beta3-adrenergic receptor
     Carteolol
      D07624  Carteolol (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2D6
   Carteolol
    D07624  Carteolol (INN)
BRITE hierarchy
Other DBs
CAS: 
51781-06-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C1x C    19.3200  -18.8300
            2   C5x C    19.3200  -20.2300
            3   N1x N    20.5800  -21.0000
            4   C8y C    21.7700  -20.2300
            5   C8y C    21.7700  -18.8300
            6   C1x C    20.5800  -18.1300
            7   C8x C    23.0300  -21.0000
            8   C8x C    24.2200  -20.2300
            9   C8x C    24.2200  -18.8300
            10  C8y C    23.0300  -18.1300
            11  O5x O    18.1300  -21.0000
            12  O2a O    23.0300  -16.7300
            13  C1b C    24.2200  -16.0300
            14  C1c C    25.4100  -16.7300
            15  C1b C    26.6000  -16.0300
            16  O1a O    25.4100  -18.1300
            17  N1b N    27.7900  -16.7300
            18  C1d C    28.9800  -16.0300
            19  C1a C    30.1700  -15.3300
            20  C1a C    29.6800  -17.2900
            21  C1a C    28.2800  -14.8400
BOND        22
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 2
            12    2  11 2
            13   10  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   14  16 1
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   18  20 1
            22   18  21 1

» Japanese version   » Back

DBGET integrated database retrieval system