KEGG   DRUG: D07689Help
Entry
D07689                      Drug                                   

Name
Chlortetracycline (INN);
Aureomycin (TN)
Formula
C22H23ClN2O8
Exact mass
478.1143
Mol weight
478.8796
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Streptomyces aureofaciens [TAX:1894]
Activity
Antibiotic;
Tetracycline
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Natural product
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Tetracyclines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB21 Chlortetracycline
      D07689  Chlortetracycline (INN)
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AA Tetracycline and derivatives
     D06AA02 Chlortetracycline
      D07689  Chlortetracycline (INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01A TETRACYCLINES
    J01AA Tetracyclines
     J01AA03 Chlortetracycline
      D07689  Chlortetracycline (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA02 Chlortetracycline
      D07689  Chlortetracycline (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Tetracyclines
     Chlortetracycline
      D07689  Chlortetracycline (INN)
BRITE hierarchy
Other DBs
CAS: 
57-62-5
PubChem: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        33
            1   C8x C    18.1300  -17.5700
            2   C8x C    18.1300  -18.9700
            3   C8y C    19.3200  -19.6700
            4   C8y C    20.5100  -18.9700
            5   C8y C    20.5100  -17.5700
            6   C8y C    19.3200  -16.9400
            7   C5x C    21.7000  -19.6700
            8   C2y C    22.8900  -18.9700
            9   C1y C    22.8900  -17.5700
            10  C1z C    21.7000  -16.9400
            11  C2y C    24.1500  -19.6700
            12  C1z C    25.3400  -18.9700
            13  C1y C    25.3400  -17.5700
            14  C1x C    24.1500  -16.9400
            15  C5x C    26.5300  -19.6700
            16  C2y C    27.7200  -18.9700
            17  C2y C    27.7200  -17.5700
            18  C1y C    26.5300  -16.9400
            19  X   Cl   19.3200  -15.5400
            20  O1a O    19.3200  -21.0700
            21  O5x O    21.7000  -21.0700
            22  O1a O    24.1500  -21.0700
            23  O5x O    26.5300  -21.0700
            24  C5a C    28.9800  -19.6700
            25  O1a O    28.9800  -16.8700
            26  N1a N    30.1700  -18.9700
            27  O5a O    28.9800  -21.0700
            28  O1a O    20.5100  -16.2400
            29  C1a C    21.7000  -15.0500
            30  N1c N    26.5300  -15.5400
            31  O1a O    25.3400  -20.3700
            32  C1a C    25.3400  -14.8400
            33  C1a C    27.7200  -14.8400
BOND        36
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16    9  14 1
            17   12  15 1
            18   15  16 1
            19   16  17 2
            20   17  18 1
            21   13  18 1
            22    6  19 1
            23    3  20 1
            24    7  21 2
            25   11  22 1
            26   15  23 2
            27   16  24 1
            28   17  25 1
            29   24  26 1
            30   24  27 2
            31   10  28 1 #Up
            32   10  29 1 #Down
            33   18  30 1 #Down
            34   12  31 1 #Down
            35   30  32 1
            36   30  33 1

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