KEGG   DRUG: Magnesium clofibrateHelp
Entry
D07724                      Drug                                   

Name
Magnesium clofibrate (INN);
Clofibric acid magnesium salt;
Clofibrate Magnesico Chobet (TN)
Formula
C20H20Cl2MgO6
Exact mass
450.0487
Mol weight
451.5802
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01946  Hypolipidemic agent
  DG01547  Fibrates
Other
 DG01733  PPAR agonist
  DG01547  Fibrates
Remark
ATC code: 
Chemical group: 
Activity
Antihyperlipidemic, Triglyceride synthesis inhibitor
Comment
Clofibrate derivative
Target
NR1C1 (PPARA) [HSA:5465] [KO:K07294]
  Pathway
PPAR signaling pathway
Adipocytokine signaling pathway
Interaction
Drug interaction
Structure map
Peroxisome proliferator-activated receptor (PPAR) agonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AB Fibrates
     C10AB01 Clofibrate
      D07724  Magnesium clofibrate (INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) alpha
     Clofibrate
      D07724  Magnesium clofibrate (INN)
BRITE hierarchy
Other DBs
CAS: 
14613-30-0
PubChem: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   C8y C    20.1600  -18.3400
            2   O2a O    21.3500  -17.6400
            3   C1d C    22.5400  -18.3400
            4   C7a C    23.8000  -17.6400
            5   O7a O    24.9900  -18.3400
            6   Z   Mg   26.3200  -17.6400
            7   O7a O    28.0000  -18.3400
            8   C7a C    29.1900  -17.6400
            9   C1d C    30.3800  -18.2700
            10  O2a O    31.6400  -17.5700
            11  C8y C    32.8300  -18.2700
            12  C1a C    21.5600  -19.3200
            13  C1a C    23.5900  -19.3200
            14  O6a O    23.8000  -16.2400
            15  O6a O    29.1900  -16.2400
            16  C1a C    29.4000  -19.3200
            17  C1a C    31.3600  -19.3200
            18  C8x C    32.8300  -19.6700
            19  C8x C    34.0200  -20.3700
            20  C8y C    35.2100  -19.6700
            21  C8x C    35.2100  -18.2700
            22  C8x C    34.0200  -17.5700
            23  C8x C    18.9000  -17.6400
            24  C8x C    17.7100  -18.3400
            25  C8y C    17.7100  -19.7400
            26  C8x C    18.9000  -20.4400
            27  C8x C    20.1600  -19.7400
            28  X   Cl   16.5200  -20.4400
            29  X   Cl   36.4700  -20.3700
BOND        30
            1     7   8 1
            2     8  15 2
            3     9  16 1
            4     8   9 1
            5     9  17 1
            6     4   5 1
            7     9  10 1
            8     2   3 1
            9    10  11 1
            10    5   6 1
            11   11  18 2
            12   18  19 1
            13   19  20 2
            14   20  21 1
            15   21  22 2
            16   22  11 1
            17    3  12 1
            18    1   2 1
            19    3  13 1
            20    6   7 1
            21    4  14 2
            22    1  23 2
            23   23  24 1
            24   24  25 2
            25   25  26 1
            26   26  27 2
            27   27   1 1
            28    3   4 1
            29   25  28 1
            30   20  29 1

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