KEGG   DRUG: D07733Help
Entry
D07733                      Drug                                   

Name
Cloxacillin (INN);
MCIPC;
Orbenin (TN)
Formula
C19H18ClN3O5S
Exact mass
435.0656
Mol weight
435.8813
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, penicillin, penicillinase-resistant
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Semisynthetic penicillin
Penicillinase [EC:3.5.2.6]-resistant penicillin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Structure map
Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CF Beta-lactamase resistant penicillins
     J01CF02 Cloxacillin
      D07733  Cloxacillin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Penicillins
     Cloxacillin
      D07733  Cloxacillin (INN)
BRITE hierarchy
Other DBs
CAS: 
61-72-3
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   C1y C    25.6200  -17.2900
            2   C5x C    25.6200  -18.6900
            3   N1y N    27.0200  -18.6900
            4   C1y C    27.0200  -17.2900
            5   C1y C    28.3500  -19.1100
            6   C1z C    29.1200  -17.9900
            7   S2x S    28.3500  -16.8700
            8   C1a C    30.1000  -18.9700
            9   C1a C    30.1000  -17.0100
            10  C6a C    28.7700  -20.4400
            11  O6a O    30.1700  -20.4400
            12  O6a O    28.0000  -21.5600
            13  N1b N    24.4300  -16.5900
            14  C5a C    23.2400  -17.2900
            15  O5x O    24.4300  -19.3200
            16  O5a O    23.2400  -18.6900
            17  C8y C    21.9800  -16.5900
            18  C8y C    21.9800  -15.1900
            19  O2x O    20.6500  -14.7700
            20  N5x N    19.8800  -15.8900
            21  C8y C    20.6500  -17.0100
            22  C1a C    23.1000  -14.3500
            23  C8y C    20.6500  -18.4100
            24  C8y C    19.3900  -19.1800
            25  C8x C    19.3900  -20.5800
            26  C8x C    20.6500  -21.2800
            27  C8x C    21.9100  -20.5800
            28  C8x C    21.9100  -19.1100
            29  X   Cl   18.2000  -18.4100
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 1
            22   20  21 2
            23   17  21 1
            24   18  22 1
            25   21  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   26  27 1
            30   27  28 2
            31   23  28 1
            32   24  29 1

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