KEGG   DRUG: D07752Help
Entry
D07752                      Drug                                   

Name
Croconazole (INN)
Formula
C18H15ClN2O
Exact mass
310.0873
Mol weight
310.7775
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antifungal;
Dermatological
Remark
Same as: 
Target
sterol 14alpha-demethylase ihibitor [KO:K05917]
  Pathway
ko00100  Steroid biosynthesis  
 
Interaction
CYP inhibition: CYP2C9 [HSA:1559]
Drug interaction
Structure map
Antifungal agents
Brite
Antiinfectives [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   sterol 14alpha-demethylase inhibitor [KO:K05917]
    Imidazoles
     Croconazole
      D07752  Croconazole (INN)
BRITE hierarchy
Other DBs
CAS: 
77175-51-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C    25.5500  -22.8200
            2   C8x C    25.9700  -21.4900
            3   N4y N    24.7800  -20.6500
            4   C8x C    23.6600  -21.4900
            5   N5x N    24.1500  -22.8200
            6   C8y C    25.9700  -17.2200
            7   C8y C    25.9700  -18.6200
            8   C8x C    27.1600  -19.3200
            9   C8x C    28.4200  -18.6200
            10  C8x C    28.4200  -17.2200
            11  C8x C    27.1600  -16.5200
            12  C8x C    19.9500  -15.1200
            13  C8x C    19.9500  -16.5200
            14  C8x C    21.1400  -17.2200
            15  C8y C    22.3300  -16.5200
            16  C8x C    22.3300  -15.1200
            17  C8y C    21.1400  -14.4200
            18  C1b C    23.5200  -17.2200
            19  O2a O    24.7800  -16.5200
            20  C2c C    24.7800  -19.2500
            21  C2a C    23.5200  -18.6200
            22  X   Cl   21.1400  -13.0200
BOND        24
            1    11   6 1
            2     1   2 2
            3     2   3 1
            4     3   4 1
            5     4   5 2
            6     5   1 1
            7    12  13 2
            8    13  14 1
            9    14  15 2
            10   15  16 1
            11   16  17 2
            12   17  12 1
            13    6   7 2
            14   15  18 1
            15    7   8 1
            16   18  19 1
            17   19   6 1
            18    8   9 2
            19    7  20 1
            20   20   3 1
            21    9  10 1
            22   20  21 2
            23   10  11 2
            24   17  22 1

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