KEGG   DRUG: D07805Help
Entry
D07805                      Drug                                   

Name
Dexfenfluramine (INN)
Formula
C12H16F3N
Exact mass
231.1235
Mol weight
231.2574
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anorexic
Remark
ATC code: 
Drug group: 
Target
serotonin transporter inhibitor [HSA:6532] [KO:K05037];
serotonin releaser
  Pathway
hsa04726  Serotonergic synapse  
 
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
   A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
    A08AA Centrally acting antiobesity products
     A08AA04 Dexfenfluramine
      D07805  Dexfenfluramine (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A3 (dopamine transporter)
     Dexfenfluramine
      D07805  Dexfenfluramine (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2D6
   Dexfenfluramine
    D07805  Dexfenfluramine (INN)
BRITE hierarchy
Other DBs
CAS: 
3239-44-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        16
            1   C1b C    19.2500  -15.4000
            2   C1c C    20.5100  -16.1000
            3   N1b N    21.7000  -15.4000
            4   C8y C    17.9900  -16.1000
            5   C8x C    16.8000  -15.4700
            6   C8y C    15.6100  -16.1700
            7   C8x C    15.6100  -17.5700
            8   C8x C    16.8000  -18.2000
            9   C8x C    17.9900  -17.5000
            10  C1d C    14.4200  -15.4000
            11  X   F    13.1600  -14.7000
            12  X   F    13.7200  -16.6600
            13  X   F    15.0500  -14.2100
            14  C1a C    20.5100  -17.5000
            15  C1b C    22.8900  -16.1000
            16  C1a C    24.1500  -15.4000
BOND        16
            1     1   2 1
            2     2   3 1
            3     1   4 1
            4     4   5 2
            5     5   6 1
            6     6   7 2
            7     7   8 1
            8     8   9 2
            9     4   9 1
            10    6  10 1
            11   10  11 1
            12   10  12 1
            13   10  13 1
            14    2  14 1 #Up
            15    3  15 1
            16   15  16 1

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