KEGG   DRUG: Dexrazoxane hydrochloride
Entry
D07807                      Drug                                   
Name
Dexrazoxane hydrochloride;
Savene (TN);
Totect (TN);
Zinecard (TN)
Product
  Generic
DEXRAZOXANE (Almaject), DEXRAZOXANE (Almaject), DEXRAZOXANE (AuroMedics Pharma LLC), DEXRAZOXANE (Breckenridge Pharmaceutical), DEXRAZOXANE (Fosun Pharma USA), DEXRAZOXANE (Gland Pharma Limited), DEXRAZOXANE (Hikma Pharmaceuticals USA)
Formula
C11H16N4O4. HCl
Exact mass
304.0938
Mol weight
304.7301
Structure
Simcomp
Remark
ATC code: V03AF02
Chemical structure group: DG01162
Product (DG01162): D03730<JP/US> D07807<US>
Efficacy
Antidote
Comment
Detoxifying agent for antineoplastic treatment
Target
TOP2 [HSA:7153 7155] [KO:K03164]
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AF Detoxifying agents for antineoplastic treatment
     V03AF02 Dexrazoxane
      D07807  Dexrazoxane hydrochloride <US>
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastic Adjuncts/Mitigators
   Dexrazoxane
    D07807  Dexrazoxane hydrochloride
Target-based classification of drugs [BR:br08310]
 Enzymes
  Isomerases (EC5)
   DNA topoisomerase
    TOP2
     D07807  Dexrazoxane hydrochloride <US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D07807
Other DBs
CAS: 149003-01-0
PubChem: 96024504
LigandBox: D07807
KCF data

ATOM        20
            1   N1x N    19.9500  -19.6700
            2   C5x C    19.9500  -18.2700
            3   C1x C    21.1400  -17.5700
            4   N1y N    22.4000  -18.2700
            5   C1x C    22.4000  -19.6700
            6   C5x C    21.1400  -20.3700
            7   O5x O    21.1400  -21.7700
            8   O5x O    18.7600  -17.5700
            9   C1b C    23.5900  -17.5700
            10  C1c C    24.7800  -18.2700
            11  N1y N    25.9700  -17.5700
            12  C1x C    25.9700  -16.1700
            13  C5x C    27.2300  -15.4700
            14  N1x N    28.4200  -16.1700
            15  C5x C    28.4200  -17.5700
            16  C1x C    27.2300  -18.2700
            17  O5x O    29.6100  -18.2700
            18  O5x O    27.2300  -14.0700
            19  C1a C    24.7800  -19.6700
            20  X   Cl   31.7100  -20.4400
BOND        20
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     6   7 2
            8     2   8 2
            9     4   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   11  16 1
            18   15  17 2
            19   13  18 2
            20   10  19 1 #Up

» Japanese version   » Back

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Drug (3)   
   KEGG DGROUP (1)   
   LigandBox (1)   
   SIDER (1)   
Chemical substance (1)   
   PubChem (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (2)   
All databases (11)   

Download RDF
DBGET integrated database retrieval system