| Entry |
|
|---|
| Name |
Dimetindene (INN);
Dimethindene |
|---|
| Formula |
C20H24N2
|
|---|
| Exact mass |
292.1939
|
|---|
| Mol weight |
292.418
|
|---|
| Structure |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist, Muscarinic acetylcholine receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA13 Dimetindene
D07853 Dimetindene (INN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AB Substituted alkylamines
R06AB03 Dimetindene
D07853 Dimetindene (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00386 Dimetindene
D07853 Dimetindene
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM2
D07853 Dimetindene (INN)
Histamine
HRH1
D07853 Dimetindene (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00386 Dimetindene
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8x C 19.8100 -18.6900
2 C8x C 19.8100 -20.0900
3 C8x C 21.0000 -20.7900
4 C8x C 21.0000 -17.9900
5 C8y C 22.2600 -18.6900
6 C8y C 22.2600 -20.0900
7 C1x C 23.5900 -20.5800
8 C2y C 24.3600 -19.3900
9 C2y C 23.5900 -18.2700
10 C1b C 25.7600 -19.3900
11 C1b C 26.4600 -20.6500
12 N1c N 27.8600 -20.6500
13 C1a C 28.5600 -21.8400
14 C1a C 28.5600 -19.4600
15 C1c C 23.5900 -16.8700
16 C8y C 24.7800 -16.1700
17 C1a C 22.3300 -16.1700
18 C8x C 25.9700 -16.8700
19 C8x C 27.1600 -16.1700
20 C8x C 27.1600 -14.7700
21 C8x C 25.9700 -14.0700
22 N5x N 24.7800 -14.7700
BOND 24
1 12 14 1
2 2 3 1
3 9 15 1
4 3 6 2
5 15 16 1
6 5 6 1
7 15 17 1
8 6 7 1
9 7 8 1
10 8 9 2
11 9 5 1
12 5 4 2
13 16 18 2
14 18 19 1
15 19 20 2
16 20 21 1
17 21 22 2
18 22 16 1
19 8 10 1
20 4 1 1
21 10 11 1
22 11 12 1
23 12 13 1
24 1 2 2
|
|---|
