| Entry |
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| Name |
Diphenylpyraline (INN)
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| Formula |
C19H23NO
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| Exact mass |
281.178
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| Mol weight |
281.392
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| Structure |
     |
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| Activity |
Antiallergic;
Histamine, H1-receptor antagonist
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| Remark |
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| Target |
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| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
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| Interaction |
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| Structure map |
| Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA07 Diphenylpyraline
D07862 Diphenylpyraline (INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H1-receptor [HSA:3269] [KO:K04149]
Diphenylpyraline [ATC:R06AA07]
D07862 Diphenylpyraline (INN)
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| Other DBs |
CAS: 147-20-6 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 21
1 C8x C 19.9500 -19.3200
2 C8x C 19.9500 -20.7200
3 C8x C 21.1400 -21.4200
4 C8x C 22.4000 -20.7200
5 C8y C 22.4000 -19.3200
6 C8x C 21.1400 -18.6200
7 C1c C 23.5900 -18.6200
8 C8y C 24.7800 -19.3200
9 O2a O 23.5900 -17.2200
10 C8x C 24.7800 -20.7200
11 C8x C 26.0400 -21.4200
12 C8x C 27.2300 -20.7200
13 C8x C 27.2300 -19.3200
14 C8x C 26.0400 -18.6200
15 C1y C 24.7800 -16.5200
16 C1x C 26.0400 -17.2200
17 C1x C 27.2300 -16.5200
18 N1y N 27.2300 -15.1200
19 C1x C 26.0400 -14.4200
20 C1x C 24.7800 -15.1200
21 C1a C 28.4200 -14.4200
BOND 23
1 4 5 1
2 5 6 2
3 6 1 1
4 8 10 2
5 10 11 1
6 11 12 2
7 12 13 1
8 13 14 2
9 14 8 1
10 9 15 1
11 5 7 1
12 7 8 1
13 1 2 2
14 7 9 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 15 1
21 2 3 1
22 18 21 1
23 3 4 2
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