KEGG   DRUG: D07862Help
Entry
D07862                      Drug                                   

Name
Diphenylpyraline (INN)
Formula
C19H23NO
Exact mass
281.178
Mol weight
281.392
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AA Aminoalkyl ethers
     R06AA07 Diphenylpyraline
      D07862  Diphenylpyraline (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Diphenylpyraline
    D07862  Diphenylpyraline (INN)
 Third-class OTC drugs
  Inorganic and organic chemicals
   Diphenylpyraline
    D07862  Diphenylpyraline (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Diphenylpyraline
      D07862  Diphenylpyraline (INN)
BRITE hierarchy
Other DBs
CAS: 
147-20-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8x C    19.9500  -19.3200
            2   C8x C    19.9500  -20.7200
            3   C8x C    21.1400  -21.4200
            4   C8x C    22.4000  -20.7200
            5   C8y C    22.4000  -19.3200
            6   C8x C    21.1400  -18.6200
            7   C1c C    23.5900  -18.6200
            8   C8y C    24.7800  -19.3200
            9   O2a O    23.5900  -17.2200
            10  C8x C    24.7800  -20.7200
            11  C8x C    26.0400  -21.4200
            12  C8x C    27.2300  -20.7200
            13  C8x C    27.2300  -19.3200
            14  C8x C    26.0400  -18.6200
            15  C1y C    24.7800  -16.5200
            16  C1x C    26.0400  -17.2200
            17  C1x C    27.2300  -16.5200
            18  N1y N    27.2300  -15.1200
            19  C1x C    26.0400  -14.4200
            20  C1x C    24.7800  -15.1200
            21  C1a C    28.4200  -14.4200
BOND        23
            1     4   5 1
            2     5   6 2
            3     6   1 1
            4     8  10 2
            5    10  11 1
            6    11  12 2
            7    12  13 1
            8    13  14 2
            9    14   8 1
            10    9  15 1
            11    5   7 1
            12    7   8 1
            13    1   2 2
            14    7   9 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  15 1
            21    2   3 1
            22   18  21 1
            23    3   4 2

» Japanese version   » Back

DBGET integrated database retrieval system