KEGG   DRUG: D07900Help
Entry
D07900                      Drug                                   

Name
Epinastine (INN);
Purivist (TN)
Formula
C16H15N3
Exact mass
249.1266
Mol weight
249.3104
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihistaminic, H1-receptor antagonist
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX24 Epinastine
      D07900  Epinastine (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01G DECONGESTANTS AND ANTIALLERGICS
    S01GX Other antiallergics
     S01GX10 Epinastine
      D07900  Epinastine (INN)
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Anti-allergy Agents
   Epinastine
    D07900  Epinastine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Drugs requiring guidance
  New approved (switch) OTC drugs
   Epinastine
    D07900  Epinastine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Epinastine
      D07900  Epinastine (INN)
BRITE hierarchy
Other DBs
CAS: 
80012-43-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C1y C    42.6766  -20.8611
            2   C8y C    41.8327  -21.9863
            3   C8y C    42.1843  -23.3225
            4   C1x C    43.4502  -23.8852
            5   N1y N    44.0832  -20.8611
            6   C8y C    44.6458  -23.3225
            7   C8y C    44.9974  -21.9160
            8   C8x C    41.1294  -24.3071
            9   C8x C    39.7932  -23.8852
            10  C8x C    39.4415  -22.5489
            11  C8x C    40.4965  -21.5644
            12  C8x C    46.2633  -21.4940
            13  C8x C    47.3182  -22.4083
            14  C8x C    46.9666  -23.8148
            15  C8x C    45.6304  -24.2368
            16  C1x C    42.1843  -19.5249
            17  N2x N    43.3096  -18.6809
            18  C2y C    44.5051  -19.4545
            19  N1a N    45.7710  -19.0326
BOND        22
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    1  16 1
            19   16  17 1
            20   17  18 2
            21    5  18 1
            22   18  19 1

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