KEGG   DRUG: D07910Help
Entry
D07910                      Drug                                   

Name
Erythromycin stinoprate (INN);
Erysec (TN)
Formula
C40H71NO14. C5H9NO3S
Exact mass
952.5178
Mol weight
953.1849
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, macrolide
Remark
ATC code: 
Target
23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor [KO:K01980]
  Pathway
ko03010  Ribosome  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576], CYP3A7 [HSA:1551]
Transporter: OAT2 [HSA:10864]
Interaction
CYP inhibition: CYP3A4 [HSA:1576], CYP3A5 [HSA:1577], CYP3A7 [HSA:1551], CYP2C19 [HSA:1557]
Transporter inhibition: ABCB1 [HSA:5243]
Drug interaction
Structure map
Macrolides and ketolides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA01 Erythromycin
      D07910  Erythromycin stinoprate (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Macrolides
   Erythromycin
    D07910  Erythromycin stinoprate (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   23S rRNA of 50S ribosomal subunit inhibitor [KO:K01980]
    Macrolides
     Erythromycin [ATC:D10AF02 J01FA01 S01AA17]
      D07910  Erythromycin stinoprate (INN)
BRITE hierarchy
Other DBs
CAS: 
84252-03-9
PubChem: 
LigandBox: 
KCF data Show

ATOM        65
            1   C1y C    13.4813  -14.8764
            2   C1z C    13.4813  -13.5435
            3   C1y C    12.2887  -15.5780
            4   O2a O    15.4456  -15.5780
            5   C1x C    12.2887  -12.8420
            6   O1a O    14.5336  -12.5613
            7   C1a C    14.7441  -13.9644
            8   C1y C    12.2887  -16.9109
            9   C1a C    11.3066  -14.5256
            10  C1y C    17.0592  -14.8764
            11  C1y C    12.2887  -11.4389
            12  O2a O    13.0604  -18.3139
            13  C1y C    11.0961  -17.6124
            14  C1y C    18.2518  -15.5780
            15  O2x O    17.0592  -13.5435
            16  C5x C    11.0961  -10.8075
            17  C1a C    13.4813  -10.8075
            18  C1y C    14.2536  -20.4849
            19  C7x C     9.9035  -16.9109
            20  C1a C    11.0961  -19.0155
            21  C1y C    19.3041  -14.9466
            22  O7a O    18.1816  -16.9810
            23  C1y C    18.2518  -12.8420
            24  C1y C     9.9035  -11.4389
            25  O5x O    11.0961   -9.4044
            26  C1x C    14.2536  -21.8178
            27  O2x O    15.4462  -19.7833
            28  O7x O     9.9035  -15.5780
            29  O6a O     8.8512  -17.8930
            30  C1x C    19.3742  -13.5435
            31  N1c N    20.4967  -15.6481
            32  C1a C    18.2518  -11.5090
            33  C1y C     9.9035  -12.8420
            34  C1a C     8.7810  -10.8075
            35  C1z C    15.4462  -22.5193
            36  C1y C    16.6389  -20.4849
            37  C1y C     8.7810  -14.8764
            38  C1z C     8.7810  -13.5435
            39  O1a O    11.0961  -13.5435
            40  C1y C    16.6389  -21.8178
            41  O2a O    15.4462  -23.7821
            42  C1a C    16.9195  -23.4313
            43  C1a C    17.8315  -19.7833
            44  C1b C     7.5884  -15.5780
            45  C1a C     7.5183  -14.1047
            46  O1a O     7.5183  -12.8420
            47  O1a O    17.8315  -22.5193
            48  C1a C    16.5687  -24.7642
            49  C1a C     7.5884  -16.7004
            50  C1a C    21.7595  -14.8764
            51  C7a C    19.3839  -17.7572
            52  O6a O    19.3839  -19.1572
            53  C1a C    21.7416  -16.3458
            54  C1b C    20.6084  -17.0904
            55  C1a C    21.7776  -17.8050
            56  C1b C    26.1791  -13.7540
            57  C1c C    27.3942  -14.4555
            58  S1a S    24.9641  -14.4555
            59  C6a C    28.5923  -13.7636
            60  O6a O    29.7823  -14.4506
            61  O6a O    28.5924  -12.3512
            62  N1b N    27.3943  -15.8584
            63  C5a C    28.5925  -16.5503
            64  C1a C    29.7822  -15.8634
            65  O5a O    28.5926  -17.9629
BOND        66
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     2   7 1 #Down
            7     3   8 1
            8     3   9 1 #Down
            9    10   4 1 #Down
            10    5  11 1
            11    8  12 1 #Down
            12    8  13 1
            13   10  14 1
            14   10  15 1
            15   11  16 1
            16   11  17 1 #Down
            17   18  12 1 #Down
            18   13  19 1
            19   13  20 1 #Up
            20   14  21 1
            21   14  22 1 #Up
            22   15  23 1
            23   16  24 1
            24   16  25 2
            25   18  26 1
            26   18  27 1
            27   19  28 1
            28   19  29 2
            29   21  30 1
            30   21  31 1 #Down
            31   23  32 1 #Down
            32   24  33 1
            33   24  34 1 #Up
            34   26  35 1
            35   27  36 1
            36   28  37 1
            37   33  38 1
            38   33  39 1 #Up
            39   35  40 1
            40   35  41 1 #Down
            41   35  42 1
            42   36  43 1 #Up
            43   37  44 1 #Down
            44   38  45 1 #Down
            45   38  46 1 #Up
            46   40  47 1 #Down
            47   41  48 1
            48   44  49 1
            49   23  30 1
            50   36  40 1
            51   37  38 1
            52   31  50 1
            53   22  51 1
            54   51  52 2
            55   31  53 1
            56   51  54 1
            57   54  55 1
            58   56  57 1
            59   56  58 1
            60   57  59 1
            61   59  60 1
            62   59  61 2
            63   57  62 1 #Up
            64   62  63 1
            65   63  64 1
            66   63  65 2

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