KEGG   DRUG: FlupirtineHelp
Entry
D07978                      Drug                                   

Name
Flupirtine (INN)
Formula
C15H17FN4O2
Exact mass
304.1336
Mol weight
304.3195
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Remark
ATC code: 
Chemical group: 
Activity
Analgesic, Antipyretic
Comment
nonopioid analgesic agent
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Glutamatergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BG Other analgesics and antipyretics
     N02BG07 Flupirtine
      D07978  Flupirtine (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Flupirtine
      D07978  Flupirtine (INN)
BRITE hierarchy
Other DBs
CAS: 
56995-20-1
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    23.5900  -18.2700
            2   C8x C    23.5900  -19.6700
            3   C8x C    24.8500  -20.3700
            4   C8y C    26.0400  -19.6700
            5   C8y C    26.0400  -18.2700
            6   N5x N    24.8500  -17.5700
            7   N1b N    22.4000  -17.5700
            8   N1a N    27.3000  -17.5700
            9   N1b N    27.3000  -20.3700
            10  C1b C    21.2100  -18.2700
            11  C7a C    28.4900  -19.6700
            12  C8y C    20.0200  -17.5700
            13  C8x C    20.0200  -16.1700
            14  C8x C    18.7600  -15.4700
            15  C8y C    17.5700  -16.1700
            16  C8x C    17.5700  -17.5700
            17  C8x C    18.7600  -18.2700
            18  X   F    16.3100  -15.4700
            19  O7a O    29.6800  -20.3700
            20  O6a O    28.4900  -18.2700
            21  C1b C    30.8700  -19.6700
            22  C1a C    32.0600  -20.3700
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     5   8 1
            9     4   9 1
            10    7  10 1
            11    9  11 1
            12   10  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   12  17 1
            19   15  18 1
            20   11  19 1
            21   11  20 2
            22   19  21 1
            23   21  22 1

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