KEGG   DRUG: D07979Help
Entry
D07979                      Drug                                   

Name
Flupirtine D-gluconate;
Katadolon (TN)
Formula
C15H17FN4O2. C6H12O7
Exact mass
500.1919
Mol weight
500.4748
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Analgesic;
Antipyretic
Remark
ATC code: 
Drug group: 
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02B OTHER ANALGESICS AND ANTIPYRETICS
    N02BG Other analgesics and antipyretics
     N02BG07 Flupirtine
      D07979  Flupirtine D-gluconate
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Flupirtine
      D07979  Flupirtine D-gluconate
BRITE hierarchy
Other DBs
CAS: 
105507-11-7
PubChem: 
LigandBox: 
KCF data Show

ATOM        35
            1   C8y C    15.8200  -18.2700
            2   C8x C    15.8200  -19.6700
            3   C8x C    17.0800  -20.3700
            4   C8y C    18.2700  -19.6700
            5   C8y C    18.2700  -18.2700
            6   N5x N    17.0800  -17.5700
            7   N1b N    14.6300  -17.5700
            8   N1a N    19.5300  -17.5700
            9   N1b N    19.5300  -20.3700
            10  C1b C    13.4400  -18.2700
            11  C7a C    20.7200  -19.6700
            12  C8y C    12.2500  -17.5700
            13  C8x C    12.2500  -16.1700
            14  C8x C    10.9900  -15.4700
            15  C8y C     9.8000  -16.1700
            16  C8x C     9.8000  -17.5700
            17  C8x C    10.9900  -18.2700
            18  X   F     8.5400  -15.4700
            19  O7a O    21.9100  -20.3700
            20  O6a O    20.7200  -18.2700
            21  C1b C    23.1000  -19.6700
            22  C1a C    24.2900  -20.3700
            23  O1a O    28.5600  -18.5500
            24  C1b C    29.7724  -17.8500
            25  C1c C    30.9849  -18.5500
            26  C1c C    32.1973  -17.8500
            27  C1c C    33.4097  -18.5500
            28  C1c C    34.6222  -17.8500
            29  C6a C    35.8346  -18.5500
            30  O1a O    30.9849  -19.9498
            31  O1a O    32.1973  -16.4500
            32  O1a O    33.4097  -19.9499
            33  O1a O    34.6222  -16.4503
            34  O6a O    37.0511  -17.8477
            35  O6a O    35.8346  -19.9500
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     5   8 1
            9     4   9 1
            10    7  10 1
            11    9  11 1
            12   10  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   12  17 1
            19   15  18 1
            20   11  19 1
            21   11  20 2
            22   19  21 1
            23   21  22 1
            24   23  24 1
            25   24  25 1
            26   25  26 1
            27   26  27 1
            28   27  28 1
            29   28  29 1
            30   25  30 1 #Down
            31   26  31 1 #Up
            32   27  32 1 #Up
            33   28  33 1 #Up
            34   29  34 1
            35   29  35 2

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