KEGG   DRUG: D07987Help
Entry
D07987                      Drug                                   

Name
Folinic acid calcium salt pentahydrate;
Leucovorin calcium pentahydrate;
Leucovorin (TN)
Formula
C20H21N7O7. Ca. 5H2O
Exact mass
601.1657
Mol weight
601.5778
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidote against folic acid antagonists
Comment
Tetrahydrofolic acid [CPD:C00101] derivative
Other map
Bile secretion
Brite
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastics, Other
   Leucovorin
    D07987  Folinic acid calcium salt pentahydrate
BRITE hierarchy
Other DBs
CAS: 
6035-45-6
PubChem: 
LigandBox: 
KCF data Show

ATOM        40
            1   C8y C    19.1336  -18.5009
            2   N1y N    20.3203  -19.1989
            3   C8y C    19.1336  -17.1746
            4   C8y C    18.0167  -19.1989
            5   C1y C    21.5768  -18.5009
            6   C4a C    20.3203  -20.5252
            7   N1x N    20.3203  -16.4765
            8   N5x N    18.0167  -16.4765
            9   N4x N    16.8300  -18.5009
            10  O5x O    18.0167  -20.5252
            11  C1x C    21.5766  -17.1746
            12  C1b C    22.9729  -19.1989
            13  O4a O    19.1336  -21.0837
            14  C8y C    16.8300  -17.1746
            15  N1b N    24.6482  -18.3613
            16  N1a N    15.7132  -16.4765
            17  C8y C    26.1839  -19.1989
            18  C8x C    26.7424  -18.0122
            19  C8x C    26.8122  -20.3158
            20  C8x C    28.1385  -18.0122
            21  C8x C    28.1385  -20.3158
            22  C8y C    28.8365  -19.1989
            23  C5a C    29.9534  -18.5707
            24  N1b N    31.3495  -19.2687
            25  O5a O    29.9532  -17.1746
            26  C1c C    32.9550  -18.5707
            27  C1b C    34.1417  -19.2687
            28  C6a C    32.9552  -17.2444
            29  C1b C    35.2586  -18.5707
            30  O6a O    34.0719  -16.6161 #-
            31  O6a O    31.7683  -16.6161
            32  C6a C    36.4453  -19.2687
            33  O6a O    36.4455  -20.8044 #-
            34  O6a O    37.5622  -18.5707
            35  Z   Ca   36.1238  -16.6846 #2+
            36  O0  O    25.3463  -24.3645
            37  O0  O    29.4648  -24.3645
            38  O0  O    33.7229  -24.2249
            39  O0  O    27.1612  -25.8304
            40  O0  O    31.9777  -25.7606
BOND        36
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     4  10 2
            10    5  11 1
            11    5  12 1
            12    6  13 2
            13    8  14 2
            14   12  15 1
            15   14  16 1
            16   15  17 1
            17   17  18 1
            18   17  19 2
            19   18  20 2
            20   19  21 1
            21   20  22 1
            22   22  23 1
            23   23  24 1
            24   23  25 2
            25   24  26 1
            26   26  27 1
            27   26  28 1
            28   27  29 1
            29   28  30 1
            30   28  31 2
            31   29  32 1
            32   32  33 1
            33   32  34 2
            34    7  11 1
            35    9  14 1
            36   21  22 2

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