| Entry |
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| Name |
Framycetin sulfate;
Neomycin B sulfate;
Isofra (TN)
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| Formula |
C23H46N6O13. H2SO4
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| Exact mass |
712.2797
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| Mol weight |
712.7222
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| Structure |
     |
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| Activity |
Antibiotic, aminoglycoside
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| Remark |
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| Target |
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO: K01977] |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AB Antiinfectives and antiseptics for local oral treatment
A01AB08 Neomycin
D07994 Framycetin sulfate
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07A INTESTINAL ANTIINFECTIVES
A07AA Antibiotics
A07AA01 Neomycin
D07994 Framycetin sulfate
B BLOOD AND BLOOD FORMING ORGANS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05C IRRIGATING SOLUTIONS
B05CA Antiinfectives
B05CA09 Neomycin
D07994 Framycetin sulfate
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX04 Neomycin
D07994 Framycetin sulfate
D09 MEDICATED DRESSINGS
D09A MEDICATED DRESSINGS
D09AA Medicated dressings with antiinfectives
D09AA01 Framycetin
D07994 Framycetin sulfate
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01G AMINOGLYCOSIDE ANTIBACTERIALS
J01GB Other aminoglycosides
J01GB05 Neomycin
D07994 Framycetin sulfate
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AX Other nasal preparations
R01AX08 Framycetin
D07994 Framycetin sulfate
R02 THROAT PREPARATIONS
R02A THROAT PREPARATIONS
R02AB Antibiotics
R02AB01 Neomycin
D07994 Framycetin sulfate
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA03 Neomycin
D07994 Framycetin sulfate
S01AA07 Framycetin
D07994 Framycetin sulfate
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA07 Neomycin
D07994 Framycetin sulfate
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA01 Neomycin
D07994 Framycetin sulfate
Antiinfectives [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
16S rRNA of 30S ribosomal subunit inhibitor [KO:K01977]
Aminoglycosides
Neomycin [ATC:A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01]
D07994 Framycetin sulfate
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| Other DBs |
CAS: 28002-70-2 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 47
1 C1y C 20.5722 -21.3409
2 C1y C 20.5722 -22.7403
3 C1y C 21.8317 -23.4399
4 C1y C 23.0211 -22.7403
5 C1y C 23.0211 -21.3409
6 O2x O 21.8317 -20.6412
7 O2a O 24.2106 -20.6412
8 C1y C 26.4496 -19.5217
9 C1y C 26.8695 -18.1923
10 O2x O 25.7499 -17.4226
11 C1y C 24.6304 -18.1923
12 C1y C 25.0503 -19.5217
13 O2a O 28.4787 -17.7724
14 O1a O 28.8986 -20.5012
15 C1y C 30.0880 -19.8015
16 C1y C 31.2775 -20.5012
17 C1x C 32.4670 -19.8015
18 C1y C 32.4670 -18.4721
19 C1y C 31.2775 -17.7724
20 C1y C 30.0880 -18.4721
21 N1a N 31.2775 -21.9006
22 N1a N 33.6565 -17.7724
23 O2a O 31.2775 -16.3731
24 C1y C 32.4670 -15.6734
25 O2x O 33.6565 -16.3731
26 C1y C 34.7760 -15.6734
27 C1y C 34.7760 -14.2740
28 C1y C 33.6565 -13.5743
29 C1y C 32.4670 -14.2740
30 C1b C 36.0354 -16.3031
31 N1a N 36.0354 -17.7025
32 N1a N 31.2075 -13.5743
33 O1a O 33.6565 -12.2449
34 O1a O 36.0354 -13.5043
35 C1b C 23.3010 -17.7724
36 O1a O 27.2893 -20.6412
37 O1a O 22.2515 -18.7520
38 C1b C 19.4527 -20.6412
39 O1a O 19.4527 -23.4399
40 N1a N 24.2106 -23.4399
41 O1a O 21.8317 -24.8393
42 N1a N 18.1933 -21.3409
43 S4a S 36.0434 -23.0244
44 O1d O 36.0434 -21.6250
45 O1d O 36.0434 -24.4238
46 O1d O 37.4428 -23.0244
47 O1d O 34.6440 -23.0244
BOND 49
1 25 26 1
2 26 27 1
3 27 28 1
4 28 29 1
5 29 24 1
6 26 30 1 #Up
7 15 14 1 #Down
8 30 31 1
9 5 7 1 #Down
10 29 32 1 #Down
11 28 33 1 #Up
12 1 2 1
13 27 34 1 #Down
14 2 3 1
15 11 35 1 #Up
16 12 7 1 #Down
17 3 4 1
18 8 36 1 #Down
19 15 16 1
20 35 37 1
21 16 17 1
22 1 38 1 #Down
23 17 18 1
24 2 39 1 #Down
25 18 19 1
26 4 40 1 #Down
27 19 20 1
28 3 41 1 #Up
29 20 15 1
30 4 5 1
31 16 21 1 #Up
32 8 9 1
33 18 22 1 #Up
34 9 10 1
35 19 23 1 #Down
36 20 13 1 #Up
37 10 11 1
38 24 23 1 #Down
39 11 12 1
40 12 8 1
41 5 6 1
42 9 13 1 #Up
43 6 1 1
44 24 25 1
45 38 42 1
46 43 44 2
47 43 45 2
48 43 46 1
49 43 47 1
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