KEGG   DRUG: GatifloxacinHelp
Entry
D08011                      Drug                                   

Name
Gatifloxacin (INN);
Gatifloxacin (TN);
Zymer (TN)
Product
  Generic
Formula
C19H22FN3O4
Exact mass
375.1594
Mol weight
375.3941
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA16 Gatifloxacin
      D08011  Gatifloxacin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE06 Gatifloxacin
      D08011  Gatifloxacin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Gatifloxacin
    D08011  Gatifloxacin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Gatifloxacin
      D08011  Gatifloxacin (INN)
BRITE hierarchy
Other DBs
CAS: 
160738-57-8
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        27
            1   C8y C    24.7800  -17.5700
            2   N4y N    25.9700  -18.2700
            3   C8y C    24.7800  -16.1700
            4   C8y C    23.5900  -18.2700
            5   C1y C    25.9700  -19.6700
            6   C8x C    27.1600  -17.5000
            7   C8y C    25.9700  -15.4700
            8   C8x C    23.5200  -15.4700
            9   C8y C    22.3300  -17.5700
            10  O2a O    23.5900  -19.6700
            11  C1x C    26.6700  -20.8600
            12  C1x C    25.2700  -20.8600
            13  C8y C    27.1600  -16.1000
            14  O5x O    25.9700  -14.0700
            15  C8y C    22.3300  -16.1700
            16  N1y N    21.2100  -18.3400
            17  C1a C    22.6100  -20.6500
            18  C6a C    28.4200  -15.4000
            19  X   F    21.1400  -15.4700
            20  C1x C    21.2100  -19.7400
            21  C1x C    20.0200  -17.6400
            22  O6a O    29.6100  -16.1700
            23  O6a O    28.4200  -14.0000
            24  C1y C    20.0200  -20.4400
            25  C1x C    18.7600  -18.3400
            26  N1x N    18.7600  -19.7400
            27  C1a C    20.0200  -21.8400
BOND        30
            1     9  15 2
            2    11  12 1
            3    25  26 1
            4     1   2 1
            5     1   3 1
            6     1   4 2
            7     2   5 1
            8     2   6 1
            9     3   7 1
            10    3   8 2
            11    4   9 1
            12    4  10 1
            13    5  11 1
            14    5  12 1
            15    6  13 2
            16    7  14 2
            17    8  15 1
            18    9  16 1
            19   10  17 1
            20   13  18 1
            21   15  19 1
            22   16  20 1
            23   16  21 1
            24   18  22 1
            25   18  23 2
            26   20  24 1
            27   21  25 1
            28   24  26 1
            29   24  27 1
            30    7  13 1

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