KEGG   DRUG: GemifloxacinHelp
Entry
D08012                      Drug                                   

Name
Gemifloxacin (INN);
Factiv (TN)
Formula
C18H20FN5O4
Exact mass
389.1499
Mol weight
389.3809
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621] [KO:K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA15 Gemifloxacin
      D08012  Gemifloxacin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Gemifloxacin
    D08012  Gemifloxacin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Gemifloxacin
      D08012  Gemifloxacin (INN)
BRITE hierarchy
Other DBs
CAS: 
204519-64-2
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        28
            1   C8y C    26.3900  -16.3800
            2   C8y C    26.3900  -17.7800
            3   N4y N    27.5800  -18.4800
            4   C8x C    28.7700  -17.7800
            5   C8y C    28.7700  -16.3800
            6   C8y C    27.5800  -15.6800
            7   C8x C    25.1300  -15.6800
            8   C8y C    23.9400  -16.3800
            9   C8y C    23.9400  -17.7800
            10  N5x N    25.1300  -18.4800
            11  C6a C    30.0300  -15.6800
            12  O6a O    31.2200  -16.3800
            13  O6a O    30.0300  -14.2800
            14  O5x O    27.5800  -14.2800
            15  X   F    22.7500  -15.6800
            16  N1y N    22.7500  -18.4800
            17  C1y C    27.5800  -19.8800
            18  C1x C    26.8800  -21.0700
            19  C1x C    28.2800  -21.0700
            20  C1x C    21.4200  -18.0600
            21  C2y C    20.5800  -19.1800
            22  C1y C    21.4200  -20.3000
            23  C1x C    22.7500  -19.8800
            24  C1b C    21.0000  -21.6300
            25  N2b N    19.1800  -19.1800
            26  O2a O    18.4800  -17.9900
            27  C1a C    17.0800  -17.9900
            28  N1a N    19.6000  -21.6300
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    2  10 1
            12    5  11 1
            13   11  12 1
            14   11  13 2
            15    6  14 2
            16    8  15 1
            17    9  16 1
            18    3  17 1
            19   17  18 1
            20   17  19 1
            21   19  18 1
            22   16  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   16  23 1
            27   22  24 1
            28   21  25 2
            29   25  26 1
            30   26  27 1
            31   24  28 1

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