KEGG   DRUG: D08013Help
Entry
D08013                      Drug                                   

Name
Gentamicin (BAN);
Gentamicin (TN)
Formula
C21H43N5O7
Exact mass
477.3162
Mol weight
477.5954
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Micromonospora echinospora [TAX:1877]
Activity
Atnibiotic, aminoglycoside
Remark
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX07 Gentamicin
      D08013  Gentamicin (BAN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB03 Gentamicin
      D08013  Gentamicin (BAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA11 Gentamicin
      D08013  Gentamicin (BAN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA14 Gentamicin
      D08013  Gentamicin (BAN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA06 Gentamicin
      D08013  Gentamicin (BAN)
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Gentamicin
    D08013  Gentamicin (BAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Aminoglycosides
     Gentamicin
      D08013  Gentamicin (BAN)
BRITE hierarchy
Other DBs
CAS: 
1403-66-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        33
            1   C1y C    25.4100  -17.7100
            2   C1y C    23.3800  -18.3400
            3   O2a O    25.6900  -18.7600
            4   C1y C    26.6000  -18.1300
            5   C1y C    22.6100  -17.3600
            6   O1a O    22.5400  -19.1100
            7   C1y C    25.9700  -19.8100
            8   C1x C    25.5500  -17.0800
            9   N1a N    27.5100  -17.5700
            10  O2a O    21.7000  -17.8500
            11  C1y C    23.8700  -17.7100
            12  C1y C    26.6700  -20.7900
            13  O2x O    27.4400  -19.8100
            14  C1y C    21.4200  -16.8000
            15  N1a N    24.2900  -16.2400
            16  C1y C    28.7700  -20.2300
            17  O1a O    25.9000  -21.5600
            18  C1x C    28.9800  -19.3200
            19  O2x O    20.9300  -15.4700
            20  C1y C    20.1600  -16.3800
            21  C1z C    29.9600  -20.6500
            22  N1b N    28.4900  -21.4900
            23  C1y C    18.6200  -16.3800
            24  C1x C    18.1300  -17.0100
            25  N1a N    19.8800  -17.5700
            26  C1a C    30.8700  -20.0900
            27  O1a O    30.5200  -21.5600
            28  C1a C    29.5400  -22.6100
            29  C1x C    17.4300  -16.0300
            30  C1c C    18.8300  -14.7700
            31  N1b N    19.8800  -14.4900
            32  C1a C    18.0600  -14.0000
            33  C1a C    20.4400  -13.2300
BOND        35
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 1
            11    7  12 1
            12    7  13 1
            13   10  14 1
            14   11  15 1
            15   12  16 1
            16   12  17 1
            17   13  18 1
            18   14  19 1
            19   14  20 1
            20   16  21 1
            21   16  22 1
            22   19  23 1
            23   20  24 1
            24   20  25 1
            25   21  26 1
            26   21  27 1
            27   22  28 1
            28   23  29 1
            29   23  30 1
            30   30  31 1
            31   30  32 1
            32   31  33 1
            33    8  11 1
            34   18  21 1
            35   24  29 1

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