| Entry |
|
|---|
| Name |
Haloperidol lactate;
Haldol (TN)
|
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C24H27ClFNO4
|
|---|
| Exact mass |
447.1613
|
|---|
| Mol weight |
447.9269
|
|---|
| Structure |
     |
|---|
| Activity |
Neuroleptic, Antipsychotic
|
|---|
| Remark |
|
|---|
| Comment |
Butyrophenone derivatives
|
|---|
| Target |
dopamine D2-receptor antagonist [HSA: 1813] [KO: K04145] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| Butyrophenones | | Butyrophenone family | | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD01 Haloperidol
D08035 Haloperidol lactate
USP drug classification [BR:br08302]
Antipsychotics
1st Generation/Typical
Haloperidol
D08035 Haloperidol lactate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
dopamine D2-receptor [HSA:1813] [KO:K04145]
Haloperidol [ATC:N05AD01]
D08035 Haloperidol lactate
 |
|---|
| Other DBs |
CAS: 75478-79-4 PubChem: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 31
1 C1b C 21.7700 -19.3200
2 C1b C 23.0300 -18.6200
3 C1b C 24.2900 -19.3200
4 N1y N 25.4800 -18.6200
5 C1x C 25.4800 -17.2200
6 C1x C 26.6700 -19.3200
7 C1x C 26.6700 -16.5200
8 C1x C 27.8600 -18.6200
9 C1z C 27.8600 -17.2200
10 C8y C 29.0500 -16.5200
11 C8x C 29.0500 -15.1900
12 C8x C 30.3100 -17.2200
13 C8x C 30.3100 -14.4900
14 C8x C 31.5000 -16.5200
15 C8y C 31.5000 -15.1900
16 X Cl 32.6900 -14.4900
17 C5a C 20.5800 -18.6200
18 C8y C 19.3900 -19.3200
19 O5a O 20.5800 -17.1500
20 C8x C 19.3900 -20.7200
21 C8x C 18.1300 -21.4200
22 C8y C 16.8700 -20.7200
23 C8x C 16.8700 -19.3200
24 C8x C 18.1300 -18.6200
25 X F 15.6800 -21.4200
26 O7a O 29.0500 -17.9200
27 C7a C 29.0500 -19.3200
28 C1c C 30.4023 -19.6823
29 C1a C 31.3870 -18.6974
30 O1a O 30.7599 -21.0175
31 O6a O 27.9393 -20.1723
BOND 33
1 9 10 1
2 10 11 1
3 10 12 2
4 11 13 2
5 12 14 1
6 13 15 1
7 15 16 1
8 8 9 1
9 14 15 2
10 1 17 1
11 1 2 1
12 17 18 1
13 2 3 1
14 17 19 2
15 3 4 1
16 4 5 1
17 4 6 1
18 5 7 1
19 6 8 1
20 18 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 23 24 1
25 24 18 2
26 7 9 1
27 22 25 1
28 9 26 1
29 26 27 1
30 27 28 1
31 28 29 1
32 28 30 1
33 27 31 2
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