KEGG   DRUG: D08041Help
Entry
D08041                      Drug                                   

Name
Homochlorcyclizine (INN)
Formula
C19H23ClN2
Exact mass
314.155
Mol weight
314.8523
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Homochlorcyclizine
      D08041  Homochlorcyclizine (INN)
BRITE hierarchy
Other DBs
CAS: 
848-53-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1x C    22.7616  -13.8610
            2   C1x C    22.6076  -12.4741
            3   C1x C    23.5569  -11.4140
            4   N1y N    24.9822  -11.6067
            5   N1y N    23.9635  -14.5699
            6   C1x C    25.6848  -12.7501
            7   C1x C    25.2764  -14.1292
            8   C1a C    25.6911  -10.4048
            9   C8y C    22.6628  -16.6378
            10  C1c C    23.9264  -16.0060
            11  C8y C    25.1283  -16.7150
            12  C8x C    25.1613  -18.1511
            13  C8x C    26.2932  -18.8600
            14  C8y C    27.4967  -18.1929
            15  C8x C    27.5337  -16.7567
            16  C8x C    26.3318  -16.0478
            17  C8x C    21.4609  -15.9289
            18  C8x C    20.2574  -16.5960
            19  C8x C    20.1957  -17.9367
            20  C8x C    21.4577  -18.6810
            21  C8x C    22.6612  -18.0138
            22  X   Cl   28.6986  -18.9018
BOND        24
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     4   8 1
            9     9  10 1
            10    5  10 1
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14   13  14 2
            15   14  15 1
            16   15  16 2
            17   11  16 1
            18    9  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23    9  21 1
            24   14  22 1

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