| Entry |
|
|---|
| Name |
Incadronic acid (INN) |
|---|
| Formula |
C8H19NO6P2
|
|---|
| Exact mass |
287.0688
|
|---|
| Mol weight |
287.1871
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Musculo-skeletal system agent
DG03232 Osteoporosis agent
DG01600 Bisphosphonate
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiresorptive, Farnesylpyrophosphate synthetase inhibitor |
|---|
| Comment |
Bisphosphonate
|
|---|
| Target |
|
|---|
| Pathway |
| hsa00900 | Terpenoid backbone biosynthesis |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG03232 Osteoporosis agent
DG01600 Bisphosphonate
DG01266 Incadronic acid
D08073 Incadronic acid
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Alkyl/Aryl transferases
FDPS
D08073 Incadronic acid (INN)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG03232 Osteoporosis agent
DG01600 Bisphosphonate
DG01266 Incadronic acid
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 17
1 C1x C 21.9883 -8.5934
2 C1x C 23.0850 -7.7298
3 C1x C 24.4503 -8.0412
4 C1y C 25.0521 -9.2943
5 C1x C 21.9883 -10.0023
6 C1x C 24.4512 -10.5615
7 C1x C 23.0850 -10.8731
8 N1b N 26.4579 -9.2908
9 C1c C 27.1688 -10.5147
10 P1b P 28.5578 -10.5111
11 P1b P 26.4762 -11.7213
12 O1c O 25.7763 -12.9336
13 O1c O 25.2639 -11.0214
14 O1c O 27.6885 -12.4213
15 O1c O 29.9577 -10.5111
16 O1c O 28.5578 -9.1112
17 O1c O 28.5578 -11.9110
BOND 17
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 4 8 1
9 8 9 1
10 9 10 1
11 9 11 1
12 11 12 1
13 11 13 1
14 11 14 2
15 10 15 1
16 10 16 1
17 10 17 2
|
|---|
