KEGG   DRUG: IndenololHelp
Entry
D08078                      Drug                                   

Name
Indenolol (INN)
Formula
C15H21NO2
Exact mass
247.1572
Mol weight
247.3327
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
Remark
Chemical group: 
Activity
Antiarrhythmic, Antihypertensive, Vasodilator, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Indenolol
      D08078  Indenolol (INN)
    beta2-adrenergic receptor
     Indenolol
      D08078  Indenolol (INN)
BRITE hierarchy
Other DBs
CAS: 
60607-68-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C1b C    16.3800  -19.8800
            2   C1c C    17.5924  -20.5800
            3   O2a O    15.1676  -20.5800
            4   C1b C    18.7879  -19.8896
            5   N1b N    19.9753  -20.5751
            6   O1a O    17.5925  -21.9798
            7   C1c C    21.1665  -19.8871
            8   C1a C    22.3560  -20.5738
            9   C1a C    21.1665  -18.4803
            10  C8y C    15.1676  -21.9800
            11  C8y C    13.9721  -22.6704
            12  C8y C    13.9722  -24.0704
            13  C8x C    15.1847  -24.7703
            14  C8x C    16.3802  -24.0799
            15  C8x C    16.3801  -22.6799
            16  C2x C    12.6405  -22.2379
            17  C2x C    11.8178  -23.3706
            18  C1x C    12.6408  -24.5032
BOND        19
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     4   5 1
            5     2   6 1
            6     5   7 1
            7     7   8 1
            8     7   9 1
            9     3  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   11  16 1
            17   16  17 2
            18   17  18 1
            19   12  18 1

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