KEGG   DRUG: D08090Help
Entry
D08090                      Drug                                   

Name
Isoprenaline (INN)
Formula
C11H17NO3
Exact mass
211.1208
Mol weight
211.2576
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator;
beta-Sympathomimetic [DS:H00079]
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Catecholamines
Target
beta1-adrenergic receptor agonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor agonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA02 Isoprenaline
      D08090  Isoprenaline (INN)
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AB Non-selective beta-adrenoreceptor agonists
     R03AB02 Isoprenaline
      D08090  Isoprenaline (INN)
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CB Non-selective beta-adrenoreceptor agonists
     R03CB01 Isoprenaline
      D08090  Isoprenaline (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Isoprenaline
      D08090  Isoprenaline (INN)
    beta2-adrenergic receptor
     Isoprenaline
      D08090  Isoprenaline (INN)
    beta3-adrenergic receptor
     Isoprenaline
      D08090  Isoprenaline (INN)
BRITE hierarchy
Other DBs
CAS: 
7683-59-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        15
            1   C8y C    24.4564  -15.8617
            2   C8x C    23.2685  -15.0930
            3   C8x C    24.4564  -17.2592
            4   C8y C    22.0108  -15.7918
            5   C8x C    23.1987  -17.8880
            6   C8y C    22.0108  -17.1194
            7   O1a O    20.8229  -15.0232
            8   O1a O    20.8229  -17.8182
            9   C1c C    25.7142  -15.1629
            10  C1b C    26.9021  -15.8617
            11  N1b N    28.0899  -15.1629
            12  C1c C    29.3477  -15.8617
            13  C1a C    30.5356  -15.1629
            14  O1a O    25.7142  -13.7654
            15  C1a C    29.3477  -17.2592
BOND        15
            1     1   2 1
            2     1   3 2
            3     2   4 2
            4     3   5 1
            5     4   6 1
            6     4   7 1
            7     6   8 1
            8     5   6 2
            9     1   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    9  14 1
            15   12  15 1

» Japanese version   » Back

DBGET integrated database retrieval system