KEGG   DRUG: D08092Help
Entry
D08092                      Drug                                   

Name
Isoxsuprine (INN);
Dilator (TN)
Formula
C18H23NO3
Exact mass
301.1678
Mol weight
301.3801
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Vasodilator, peripheric;
beta-Sympathomimetic
Remark
ATC code: 
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C04 PERIPHERAL VASODILATORS
   C04A PERIPHERAL VASODILATORS
    C04AA 2-amino-1-phenylethanol derivatives
     C04AA01 Isoxsuprine
      D08092  Isoxsuprine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor [HSA:154] [KO:K04142]
     Isoxsuprine [ATC:C04AA01]
      D08092  Isoxsuprine (INN)
BRITE hierarchy
Other DBs
CAS: 
395-28-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    20.5100  -17.5700
            2   C1c C    21.7700  -18.2700
            3   C1c C    22.9600  -17.5700
            4   N1b N    24.1500  -18.2700
            5   C1c C    25.4100  -17.5700
            6   C1b C    26.6000  -18.2700
            7   O2a O    27.7900  -17.5700
            8   C1a C    22.9600  -16.1700
            9   C1a C    25.4100  -16.1700
            10  C8y C    29.0500  -18.2700
            11  C8x C    29.0500  -19.6700
            12  C8x C    30.2400  -20.3700
            13  C8x C    31.4300  -19.6700
            14  C8x C    31.4300  -18.2700
            15  C8x C    30.2400  -17.5700
            16  O1a O    21.7700  -19.6700
            17  C8x C    20.5100  -16.2400
            18  C8x C    19.3200  -15.5400
            19  C8y C    18.1300  -16.2400
            20  C8x C    18.1300  -17.6400
            21  C8x C    19.3200  -18.3400
            22  O1a O    16.8700  -15.5400
BOND        23
            1     5   6 1
            2     2   3 1
            3     6   7 1
            4    10  11 2
            5    11  12 1
            6    12  13 2
            7    13  14 1
            8    14  15 2
            9    15  10 1
            10    2  16 1
            11    3   8 1
            12    3   4 1
            13    5   9 1
            14    1   2 1
            15    7  10 1
            16    1  17 2
            17   17  18 1
            18   18  19 2
            19   19  20 1
            20   20  21 2
            21   21   1 1
            22    4   5 1
            23   19  22 1

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