KEGG   DRUG: D08120Help
Entry
D08120                      Drug                                   

Name
Levofloxacin (INN);
Cravit (TN);
Levaquin (TN)
Formula
C18H20FN3O4
Exact mass
361.1438
Mol weight
361.3675
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, gyrase inhibitor
Remark
Same as: 
ATC code: 
Drug group: 
Target
DNA gyrase inhibitor [KO:K02469 K02470];
topoisomerase IV inhibitor [KO:K02621 K02622]
Metabolism
Transporter: SLCO1A2 [HSA:6579]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA12 Levofloxacin
      D08120  Levofloxacin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE05 Levofloxacin
      D08120  Levofloxacin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Levofloxacin
    D08120  Levofloxacin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Levofloxacin
      D08120  Levofloxacin (INN)
BRITE hierarchy
Other DBs
CAS: 
100986-85-4
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8y C    25.4100  -18.2700
            2   C8y C    24.2200  -18.9700
            3   C8y C    25.4100  -16.8700
            4   N4y N    26.6700  -18.9700
            5   C8y C    23.0300  -18.2700
            6   O2x O    24.2200  -20.3700
            7   C8y C    26.6700  -16.1700
            8   C8x C    24.2200  -16.1700
            9   C8x C    27.8600  -18.2700
            10  C1y C    26.6700  -20.3700
            11  N1y N    21.7700  -18.9700
            12  C8y C    23.0300  -16.8700
            13  C1x C    25.4100  -21.0700
            14  C8y C    27.8600  -16.8700
            15  O5x O    26.6700  -14.7700
            16  C1a C    27.8600  -21.0700
            17  C1x C    21.7700  -20.3700
            18  C1x C    20.5800  -18.2700
            19  X   F    21.7700  -16.1700
            20  C6a C    29.0500  -16.1700
            21  C1x C    20.5800  -21.0700
            22  C1x C    19.3900  -18.9700
            23  O6a O    30.2400  -16.8700
            24  O6a O    29.0500  -14.7700
            25  N1y N    19.3900  -20.3700
            26  C1a C    18.1300  -21.0700
BOND        29
            1    25  26 1
            2     8  12 2
            3     9  14 2
            4    10  13 1
            5    22  25 1
            6     1   2 1
            7     1   3 2
            8     1   4 1
            9     2   5 2
            10    2   6 1
            11    3   7 1
            12    3   8 1
            13    4   9 1
            14    4  10 1
            15    5  11 1
            16    5  12 1
            17    6  13 1
            18    7  14 1
            19    7  15 2
            20   10  16 1 #Up
            21   11  17 1
            22   11  18 1
            23   12  19 1
            24   14  20 1
            25   17  21 1
            26   18  22 1
            27   20  23 1
            28   20  24 2
            29   21  25 1

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