KEGG   DRUG: D08125Help
Entry
D08125                      Drug                                   

Name
Levothyroxine (BAN);
Forthyron (TN)
Formula
C15H11I4NO4
Exact mass
776.6867
Mol weight
776.87
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Thyroid hormone [DS:H00081]
Remark
Same as: 
Target
thyroid hormone receptor, alpha agonist [HSA:7067] [KO:K05547];
thyroid hormone receptor, beta agonist [HSA:7068] [KO:K08362]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Antineoplastics - hormones
Brite
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Thyroid)
  Levothyroxine
   D08125  Levothyroxine (BAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Thyroid hormone receptor (THR)
    thyroid hormone receptor, alpha
     Levothyroxine
      D08125  Levothyroxine (BAN)
    thyroid hormone receptor, beta
     Levothyroxine
      D08125  Levothyroxine (BAN)
BRITE hierarchy
Other DBs
CAS: 
51-48-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8y C    27.0900  -18.6200
            2   O2a O    25.9000  -17.9200
            3   C8x C    27.0900  -20.0200
            4   C8x C    28.3500  -17.9200
            5   C8y C    24.7100  -17.2200
            6   C8y C    28.3500  -20.7200
            7   C8y C    29.5400  -18.6200
            8   C8y C    23.5200  -17.9200
            9   C8y C    24.7100  -15.8200
            10  C8y C    29.5400  -20.0200
            11  X   I    28.3500  -22.1200
            12  X   I    30.7300  -17.8500
            13  C8x C    22.2600  -17.2200
            14  X   I    23.5200  -19.3200
            15  C8x C    23.5200  -15.1200
            16  X   I    25.9000  -15.1200
            17  O1a O    30.8000  -20.6500
            18  C8y C    22.2600  -15.8200
            19  C1b C    21.0700  -15.1200
            20  C1c C    19.8800  -15.8200
            21  C6a C    18.6900  -15.1200
            22  N1a N    19.8800  -17.2200
            23  O6a O    18.6900  -13.7200
            24  O6a O    17.5000  -15.8200
BOND        25
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     4   7 2
            7     5   8 1
            8     5   9 2
            9     6  10 2
            10    6  11 1
            11    7  12 1
            12    8  13 2
            13    8  14 1
            14    9  15 1
            15    9  16 1
            16   10  17 1
            17   13  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   20  22 1 #Down
            22   21  23 2
            23   21  24 1
            24    7  10 1
            25   15  18 2

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