| Entry |
|
|---|
| Name |
Levothyroxine (BAN);
Forthyron (TN)
|
|---|
| Formula |
C15H11I4NO4
|
|---|
| Exact mass |
776.6867
|
|---|
| Mol weight |
776.87
|
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| Structure |
     |
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| Activity |
|
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| Remark |
|
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| Target |
thyroid hormone receptor, alpha agonist [HSA: 7067] [KO: K05547]; thyroid hormone receptor, beta agonist [HSA: 7068] [KO: K08362] |
|---|
| Pathway |
hsa04080 Neuroactive ligand-receptor interaction | |
|
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| Interaction |
|
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| Structure map |
| Antineoplastics - hormones |
|
|---|
| Brite |
USP drug classification [BR:br08302]
Hormonal Agents
Hormonal Agents, Stimulant / Replacement / Modifying (Thyroid)
Thyroid Replacements
Levothyroxine
D08125 Levothyroxine (BAN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Thyroid hormone receptor (THR)
thyroid hormone receptor, alpha [HSA:7067] [KO:K05547]
Levothyroxine
D08125 Levothyroxine (BAN)
thyroid hormone receptor, beta [HSA:7068] [KO:K08362]
Levothyroxine
D08125 Levothyroxine (BAN)
 |
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| Other DBs |
CAS: 51-48-9 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 24
1 C8y C 27.0900 -18.6200
2 O2a O 25.9000 -17.9200
3 C8x C 27.0900 -20.0200
4 C8x C 28.3500 -17.9200
5 C8y C 24.7100 -17.2200
6 C8y C 28.3500 -20.7200
7 C8y C 29.5400 -18.6200
8 C8y C 23.5200 -17.9200
9 C8y C 24.7100 -15.8200
10 C8y C 29.5400 -20.0200
11 X I 28.3500 -22.1200
12 X I 30.7300 -17.8500
13 C8x C 22.2600 -17.2200
14 X I 23.5200 -19.3200
15 C8x C 23.5200 -15.1200
16 X I 25.9000 -15.1200
17 O1a O 30.8000 -20.6500
18 C8y C 22.2600 -15.8200
19 C1b C 21.0700 -15.1200
20 C1c C 19.8800 -15.8200
21 C6a C 18.6900 -15.1200
22 N1a N 19.8800 -17.2200
23 O6a O 18.6900 -13.7200
24 O6a O 17.5000 -15.8200
BOND 25
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1
8 5 9 2
9 6 10 2
10 6 11 1
11 7 12 1
12 8 13 2
13 8 14 1
14 9 15 1
15 9 16 1
16 10 17 1
17 13 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 20 22 1 #Down
22 21 23 2
23 21 24 1
24 7 10 1
25 15 18 2
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