KEGG   DRUG: D08128Help
Entry
D08128                      Drug                                   

Name
Liothyronine (INN);
Thyrolar (TN)
Formula
C15H12I3NO4
Exact mass
650.79
Mol weight
650.9735
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Thyroid hormone
Remark
Same as: 
Target
thyroid hormone receptor, alpha agonist [HSA:7067] [KO:K05547];
thyroid hormone receptor, beta agonist [HSA:7068] [KO:K08362]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Antineoplastics - hormones
Brite
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Thyroid)
  Liothyronine
   D08128  Liothyronine (INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Thyroid hormone receptor (THR)
    thyroid hormone receptor, alpha
     Liothyronine
      D08128  Liothyronine (INN)
    thyroid hormone receptor, beta
     Liothyronine
      D08128  Liothyronine (INN)
BRITE hierarchy
Other DBs
CAS: 
6893-02-3
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C8y C    24.7800  -17.9200
            2   O2a O    25.9700  -18.6200
            3   C8y C    23.5900  -18.6200
            4   C8y C    24.7800  -16.5200
            5   C8y C    27.2300  -19.3200
            6   C8x C    22.3300  -17.9200
            7   X   I    23.5900  -20.0200
            8   C8x C    23.5900  -15.8200
            9   X   I    25.9700  -15.8200
            10  C8x C    28.4200  -18.6200
            11  C8x C    27.2300  -20.7200
            12  C8y C    22.3300  -16.5200
            13  C8y C    29.6100  -19.3200
            14  C8x C    28.4200  -21.4200
            15  C1b C    21.1400  -15.8200
            16  C8y C    29.6100  -20.7200
            17  X   I    30.8700  -18.6200
            18  C1c C    19.9500  -16.5200
            19  O1a O    30.8700  -21.4200
            20  C6a C    18.6900  -15.8200
            21  N1a N    19.9500  -17.9200
            22  O6a O    17.5000  -16.5200
            23  O6a O    18.6900  -14.4200
BOND        24
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 2
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12   10  13 2
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   15  18 1
            18   16  19 1
            19   18  20 1
            20   18  21 1 #Down
            21   20  22 1
            22   20  23 2
            23    8  12 1
            24   14  16 2

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