KEGG   DRUG: D08130Help
Entry
D08130                      Drug                                   

Name
Lisdexamfetamine (INN)
Formula
C15H25N3O
Exact mass
263.1998
Mol weight
263.3785
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Drug group: 
Comment
prodrug, active substance: Amphetamine [DR:D07445]
Target
noradrenalin transporter inhibitor [HSA:6530] [KO:K05035];
dopamine transporter inhibitor [HSA:6531] [KO:K05036]
  Pathway
hsa04728  Dopaminergic synapse
hsa05031  Amphetamine addiction  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA12 Lisdexamfetamine
      D08130  Lisdexamfetamine (INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Amphetamines
   Lisdexamfetamine
    D08130  Lisdexamfetamine (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Lisdexamfetamine
      D08130  Lisdexamfetamine (INN)
    SLC6A3 (dopamine transporter)
     Lisdexamfetamine
      D08130  Lisdexamfetamine (INN)
BRITE hierarchy
Other DBs
CAS: 
608137-32-2
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        19
            1   C8x C    17.0100  -17.9200
            2   C8x C    17.0100  -19.3200
            3   C8x C    18.2000  -20.0200
            4   C8x C    19.4600  -19.3200
            5   C8y C    19.4600  -17.9200
            6   C8x C    18.2000  -17.2200
            7   C1b C    20.6500  -17.2200
            8   C1c C    21.8400  -17.9200
            9   N1b N    23.0300  -17.2200
            10  C1a C    21.8400  -19.3200
            11  C5a C    24.2200  -17.9200
            12  C1c C    25.4100  -17.2200
            13  O5a O    24.2200  -19.3200
            14  C1b C    26.6000  -17.9200
            15  C1b C    27.7900  -17.2200
            16  C1b C    28.9800  -17.9200
            17  C1b C    30.1700  -17.2200
            18  N1a N    31.3600  -17.9200
            19  N1a N    25.4100  -15.8200
BOND        19
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    8  10 1 #Up
            11    9  11 1
            12   11  12 1
            13   11  13 2
            14   12  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   12  19 1 #Up

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