KEGG   DRUG: D08131Help
Entry
D08131                      Drug                                   

Name
Lisinopril (INN);
Zestril (TN)
Formula
C21H31N3O5
Exact mass
405.2264
Mol weight
405.4879
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
ACE-inhibitor;
Antihypertensive
Remark
ATC code: 
Drug group: 
Target
angiotensin-converting enzyme (ACE) inhibitor [HSA:1636] [KO:K01283]
  Pathway
hsa04614  Renin-angiotensin system  
 
Interaction
Drug interaction
Structure map
Renin-angiotensin system inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09A ACE INHIBITORS, PLAIN
    C09AA ACE inhibitors, plain
     C09AA03 Lisinopril
      D08131  Lisinopril (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Angiotensin-converting Enzyme (ACE) Inhibitors
   Lisinopril
    D08131  Lisinopril (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   angiotensin-converting enzyme (ACE)
    Lisinopril
     D08131  Lisinopril (INN)
BRITE hierarchy
Other DBs
CAS: 
76547-98-3
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   N1y N    28.4900  -18.5500
            2   C1y C    29.6100  -19.3900
            3   C5a C    27.3000  -19.2500
            4   C1x C    28.9100  -17.2200
            5   C1x C    30.7300  -18.5500
            6   C6a C    29.6100  -20.7900
            7   C1c C    26.0400  -18.5500
            8   O5a O    27.3000  -20.6500
            9   C1x C    30.3100  -17.2200
            10  O6a O    30.8000  -21.4900
            11  O6a O    28.3500  -21.4900
            12  N1b N    24.8500  -19.2500
            13  C1b C    26.0400  -17.1500
            14  C1c C    23.6600  -18.5500
            15  C1b C    27.3000  -16.4500
            16  C1b C    22.4000  -19.2500
            17  C6a C    23.6600  -17.1500
            18  C1b C    27.3000  -15.0500
            19  C1b C    21.2100  -18.5500
            20  O6a O    24.8500  -16.4500
            21  O6a O    22.4000  -16.4500
            22  C1b C    26.0400  -14.3500
            23  C8y C    20.0200  -19.2500
            24  N1a N    24.8500  -15.0500
            25  C8x C    20.0200  -20.6500
            26  C8x C    18.7600  -18.5500
            27  C8x C    18.7600  -21.3500
            28  C8x C    17.5700  -19.2500
            29  C8x C    17.5700  -20.6500
BOND        30
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     6  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 1 #Up
            13   12  14 1
            14   13  15 1
            15   14  16 1
            16   14  17 1 #Up
            17   15  18 1
            18   16  19 1
            19   17  20 1
            20   17  21 2
            21   18  22 1
            22   19  23 1
            23   22  24 1
            24   23  25 1
            25   23  26 2
            26   25  27 2
            27   26  28 1
            28   27  29 1
            29    5   9 1
            30   28  29 2

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