KEGG   DRUG: D08183Help
Entry
D08183                      Drug                                   

Name
Mepyramine (INN)
Formula
C17H23N3O
Exact mass
285.1841
Mol weight
285.384
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
Same as: 
ATC code: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA02 Mepyramine
      D08183  Mepyramine (INN)
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AC Substituted ethylene diamines
     R06AC01 Mepyramine
      D08183  Mepyramine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor [HSA:3269] [KO:K04149]
     Mepyramine [ATC:D04AA02 R06AC01]
      D08183  Mepyramine (INN)
BRITE hierarchy
Other DBs
CAS: 
91-84-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8x C    20.5100  -16.8700
            2   C8y C    20.5100  -18.2700
            3   C8x C    21.7700  -18.9700
            4   C8x C    22.9600  -18.2700
            5   C8y C    22.9600  -16.8700
            6   C8x C    21.7700  -16.1700
            7   O2a O    19.3200  -18.9700
            8   C1a C    18.1300  -18.2700
            9   C1b C    24.2200  -16.1700
            10  N1c N    25.4100  -16.8700
            11  C1b C    26.6000  -16.1700
            12  C1b C    27.7900  -16.8700
            13  C8y C    25.4100  -18.2700
            14  N5x N    24.1500  -19.0400
            15  C8x C    24.1500  -20.4400
            16  C8x C    25.4100  -21.1400
            17  C8x C    26.6000  -20.3700
            18  C8x C    26.6000  -18.9700
            19  N1c N    28.9800  -16.1700
            20  C1a C    30.1700  -16.8700
            21  C1a C    28.9800  -14.7700
BOND        22
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     5   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   10  13 1
            14   13  14 2
            15   14  15 1
            16   15  16 2
            17   16  17 1
            18   17  18 2
            19   13  18 1
            20   12  19 1
            21   19  20 1
            22   19  21 1

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