KEGG   DRUG: D08184Help
Entry
D08184                      Drug                                   

Name
Mepyramine theophyllineacetate;
Fluidasa (TN)
Formula
C17H23N3O. C9H10N4O4
Exact mass
523.2543
Mol weight
523.5841
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA02 Mepyramine
      D08184  Mepyramine theophyllineacetate
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AC Substituted ethylene diamines
     R06AC01 Mepyramine
      D08184  Mepyramine theophyllineacetate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Mepyramine
      D08184  Mepyramine theophyllineacetate
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Others
   Purine alkaloids
    D08184  Mepyramine theophyllineacetate
BRITE hierarchy
Other DBs
CAS: 
57383-74-1
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        38
            1   C8x C    15.0500  -16.8700
            2   C8y C    15.0500  -18.2700
            3   C8x C    16.3100  -18.9700
            4   C8x C    17.5000  -18.2700
            5   C8y C    17.5000  -16.8700
            6   C8x C    16.3100  -16.2400
            7   O2a O    13.8600  -18.9700
            8   C1a C    12.6700  -18.2700
            9   C1b C    18.8300  -16.2400
            10  N1c N    20.0200  -16.8700
            11  C1b C    21.2100  -16.2400
            12  C1b C    22.4000  -16.8700
            13  C8y C    20.0200  -18.2700
            14  N5x N    18.7600  -19.0400
            15  C8x C    18.7600  -20.4400
            16  C8x C    20.0200  -21.1400
            17  C8x C    21.2100  -20.3700
            18  C8x C    21.2100  -18.9700
            19  N1c N    23.5900  -16.2400
            20  C1a C    24.7800  -16.8700
            21  C1a C    23.5900  -14.7700
            22  C8y C    34.5100  -19.5300
            23  N4y N    34.5100  -18.1300
            24  C8y C    33.3200  -17.4300
            25  C8y C    32.0600  -18.1300
            26  C8y C    32.0600  -19.5300
            27  N4y N    33.3200  -20.2300
            28  N4y N    30.7300  -17.7100
            29  C8x C    29.9600  -18.8300
            30  N5x N    30.7300  -19.9500
            31  O5x O    35.7000  -20.2300
            32  O5x O    33.3200  -16.0300
            33  C1a C    35.7000  -17.4300
            34  C1a C    33.3200  -21.6300
            35  C1b C    30.7300  -16.3100
            36  C6a C    29.5400  -15.6100
            37  O6a O    28.3500  -16.3100
            38  O6a O    29.5400  -14.2100
BOND        40
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     5   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   10  13 1
            14   13  14 2
            15   14  15 1
            16   15  16 2
            17   16  17 1
            18   17  18 2
            19   13  18 1
            20   12  19 1
            21   19  20 1
            22   19  21 1
            23   22  23 1
            24   23  24 1
            25   24  25 1
            26   25  26 2
            27   26  27 1
            28   22  27 1
            29   25  28 1
            30   28  29 1
            31   29  30 2
            32   26  30 1
            33   22  31 2
            34   24  32 2
            35   23  33 1
            36   27  34 1
            37   28  35 1
            38   35  36 1
            39   36  37 1
            40   36  38 2

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