KEGG   DRUG: D08185Help
Entry
D08185                      Drug                                   

Name
Meropenem (INN);
MEPM;
Merrem I.V. (TN);
Meronem (TN)
Formula
C17H25N3O5S
Exact mass
383.1515
Mol weight
383.4625
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, beta-lactam
Remark
ATC code: 
Drug group: 
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DH Carbapenems
     J01DH02 Meropenem
      D08185  Meropenem (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Other
   Meropenem
    D08185  Meropenem (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Carbapenems
     Meropenem
      D08185  Meropenem (INN)
BRITE hierarchy
Other DBs
CAS: 
96036-03-2
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C1y C    25.8300  -18.6900
            2   C1y C    19.5300  -16.8000
            3   C5x C    19.5300  -18.1300
            4   N1y N    20.7900  -18.1300
            5   C1y C    20.7900  -16.8000
            6   C2y C    22.1200  -18.5500
            7   C2y C    22.8900  -17.5000
            8   C1y C    22.1200  -16.3800
            9   C6a C    22.5400  -19.8800
            10  O6a O    23.8700  -19.8800
            11  O6a O    21.7700  -20.9300
            12  S2a S    25.2000  -17.5000
            13  C1a C    22.5400  -15.1200
            14  C1c C    18.3400  -16.1000
            15  C1a C    17.0800  -16.8000
            16  O5x O    18.3400  -18.8300
            17  O1a O    18.3400  -14.7000
            18  C1x C    25.4800  -20.0200
            19  N1x N    26.6000  -20.7900
            20  C1y C    27.7200  -19.9500
            21  C1x C    27.2300  -18.6900
            22  C5a C    29.1200  -19.9500
            23  O5a O    29.8200  -21.2100
            24  C1a C    31.2200  -18.7600
            25  N1c N    29.8200  -18.7600
            26  C1a C    29.1200  -17.5700
BOND        28
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     2   5 1
            5     4   6 1
            6     6   7 2
            7     7   8 1
            8     5   8 1
            9     6   9 1
            10    9  10 1
            11    9  11 2
            12    7  12 1
            13    8  13 1 #Up
            14    2  14 1
            15   14  15 1
            16    3  16 2
            17   14  17 1 #Up
            18    1  12 1 #Up
            19    1  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23    1  21 1
            24   20  22 1 #Up
            25   22  23 2
            26   24  25 1
            27   22  25 1
            28   25  26 1

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