KEGG   DRUG: MetixeneHelp
Entry
D08209                      Drug                                   

Name
Metixene (INN)
Formula
C20H23NS
Exact mass
309.1551
Mol weight
309.4683
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
 DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: 
Chemical group: 
Activity
Antiperkinsonian, Central anticholinergic
Target
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA03 Metixene
      D08209  Metixene (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Metixene
    D08209  Metixene (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Metixene
      D08209  Metixene (INN)
BRITE hierarchy
Other DBs
CAS: 
4969-02-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C    19.0400  -19.2500
            2   C8x C    19.0400  -20.6500
            3   C8x C    20.3000  -21.4200
            4   C8x C    20.3000  -18.5500
            5   C8y C    21.4900  -19.2500
            6   C8y C    21.4900  -20.6500
            7   S2x S    22.6800  -21.4200
            8   C1y C    22.6800  -18.6200
            9   C8y C    23.9400  -19.3200
            10  C8y C    23.9400  -20.7200
            11  C8x C    25.1300  -21.4200
            12  C8x C    26.3200  -20.7200
            13  C8x C    26.3200  -19.3200
            14  C8x C    25.1300  -18.6200
            15  C1b C    22.6800  -17.2200
            16  C1y C    23.9400  -16.5200
            17  C1x C    25.1300  -17.2200
            18  N1y N    26.3200  -16.5200
            19  C1x C    26.3200  -15.1200
            20  C1x C    25.1300  -14.4200
            21  C1x C    23.9400  -15.1200
            22  C1a C    27.5800  -17.2200
BOND        25
            1     4   1 1
            2     9  10 2
            3    10  11 1
            4    11  12 2
            5    12  13 1
            6    13  14 2
            7    14   9 1
            8     8  15 1
            9     1   2 2
            10   15  16 1
            11    5   6 1
            12    6   7 1
            13    7  10 1
            14    9   8 1
            15    8   5 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 1
            20   20  21 1
            21   21  16 1
            22    2   3 1
            23   18  22 1
            24    3   6 2
            25    5   4 2

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