KEGG   DRUG: D08212Help
Entry
D08212                      Drug                                   

Name
Trimazosin (INN)
Formula
C20H29N5O6
Exact mass
435.2118
Mol weight
435.4742
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
ATC code: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
    C02CA Alpha-adrenoreceptor antagonists
     C02CA03 Trimazosin
      D08212  Trimazosin (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
     Trimazosin [ATC:C02CA03]
      D08212  Trimazosin (INN)
BRITE hierarchy
Other DBs
CAS: 
35795-16-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C8y C    29.9600  -20.0900
            2   C8y C    29.9600  -18.6900
            3   C8x C    31.1500  -20.7900
            4   C8y C    28.7700  -20.7900
            5   N5x N    28.7700  -17.9900
            6   C8y C    31.1500  -17.9900
            7   C8y C    32.3400  -20.0900
            8   N5x N    27.5100  -20.0900
            9   N1a N    28.7700  -22.1900
            10  C8y C    27.5100  -18.6900
            11  C8y C    32.3400  -18.6900
            12  O2a O    33.6000  -20.7900
            13  N1y N    26.3200  -17.9900
            14  O2a O    33.6000  -17.9900
            15  C1a C    34.7900  -20.0900
            16  C1x C    26.3200  -16.5900
            17  C1x C    25.1300  -18.6900
            18  C1a C    34.7900  -18.6900
            19  C1x C    25.1300  -15.8900
            20  C1x C    23.8700  -17.9900
            21  N1y N    23.8700  -16.5900
            22  C7a C    22.6800  -15.8900
            23  O7a O    21.4200  -16.5900
            24  O6a O    22.6800  -14.4900
            25  O2a O    31.1500  -16.5900
            26  C1a C    32.4100  -15.8900
            27  C1b C    20.2300  -15.8900
            28  C1d C    19.0400  -16.5900
            29  C1a C    17.8500  -17.2900
            30  O1a O    18.3400  -15.4000
            31  C1a C    19.7400  -17.8500
BOND        33
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 2
            8     4   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1
            12   10  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   14  18 1
            18   16  19 1
            19   17  20 1
            20   19  21 1
            21   21  22 1
            22   22  23 1
            23   22  24 2
            24    7  11 1
            25    8  10 1
            26   20  21 1
            27    6  25 1
            28   25  26 1
            29   23  27 1
            30   27  28 1
            31   28  29 1
            32   28  30 1
            33   28  31 1

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