KEGG   DRUG: MilnacipranHelp
Entry
D08222                      Drug                                   

Name
Milnacipran (INN)
Formula
C15H22N2O
Exact mass
246.1732
Mol weight
246.348
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01658  Serotonin and norepinephrine reuptake inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI)
Comment
selective serotonin norepinephrine reuptake inhibitor (SNRI)
Target
SLC6A4 (HTT) [HSA:6532] [KO:K05037];
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
  Pathway
Serotonergic synapse
Interaction
Drug interaction
Structure map
Antidepressants
Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX17 Milnacipran
      D08222  Milnacipran (INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Fibromyalgia Agents
   Milnacipran
    D08222  Milnacipran (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Milnacipran
      D08222  Milnacipran (INN)
    SLC6A4 (serotonin transporter)
     Milnacipran
      D08222  Milnacipran (INN)
BRITE hierarchy
Other DBs
CAS: 
92623-85-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8x C    20.5100  -15.7500
            2   C8x C    20.5100  -17.1500
            3   C8x C    21.7000  -17.8500
            4   C8y C    22.9600  -17.1500
            5   C8x C    22.9600  -15.7500
            6   C8x C    21.7000  -15.0500
            7   C5a C    24.3600  -17.1500
            8   C1x C    22.9600  -19.6000
            9   C1y C    24.3600  -19.6000
            10  C1z C    23.6600  -18.3400
            11  C1b C    25.0600  -20.7900
            12  O5a O    24.3600  -15.7500
            13  N1c N    25.7600  -17.1500
            14  C1b C    26.4600  -15.9600
            15  C1b C    26.4600  -18.3400
            16  C1a C    27.8600  -18.3400
            17  C1a C    27.8600  -15.9600
            18  N1a N    26.4600  -20.7900
BOND        19
            1     8  10 1
            2    10   9 1
            3     3   4 2
            4     9  11 1 #Up
            5    10   4 1 #Down
            6    10   7 1
            7     4   5 1
            8     7  12 2
            9     5   6 2
            10    7  13 1
            11    6   1 1
            12   13  14 1
            13   13  15 1
            14   15  16 1
            15    1   2 2
            16   14  17 1
            17    2   3 1
            18   11  18 1
            19    8   9 1

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