KEGG   DRUG: D08222Help
Entry
D08222                      Drug                                   

Name
Milnacipran (INN)
Formula
C15H22N2O
Exact mass
246.1732
Mol weight
246.348
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
ATC code: 
Drug group: 
Comment
selective serotonin norepinephrine reuptake inhibitor (SNRI)
Target
serotonin transporter inhibitor [HSA:6532] [KO:K05037];
noradrenalin transporter inhibitor [HSA:6530] [KO:K05035]
  Pathway
hsa04726  Serotonergic synapse  
 
Interaction
Drug interaction
Structure map
Antidepressants
Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX17 Milnacipran
      D08222  Milnacipran (INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Fibromyalgia Agents
   Milnacipran
    D08222  Milnacipran (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Milnacipran
      D08222  Milnacipran (INN)
    SLC6A4 (serotonin transporter)
     Milnacipran
      D08222  Milnacipran (INN)
BRITE hierarchy
Other DBs
CAS: 
92623-85-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8x C    20.5100  -15.7500
            2   C8x C    20.5100  -17.1500
            3   C8x C    21.7000  -17.8500
            4   C8y C    22.9600  -17.1500
            5   C8x C    22.9600  -15.7500
            6   C8x C    21.7000  -15.0500
            7   C5a C    24.3600  -17.1500
            8   C1x C    22.9600  -19.6000
            9   C1y C    24.3600  -19.6000
            10  C1z C    23.6600  -18.3400
            11  C1b C    25.0600  -20.7900
            12  O5a O    24.3600  -15.7500
            13  N1c N    25.7600  -17.1500
            14  C1b C    26.4600  -15.9600
            15  C1b C    26.4600  -18.3400
            16  C1a C    27.8600  -18.3400
            17  C1a C    27.8600  -15.9600
            18  N1a N    26.4600  -20.7900
BOND        19
            1     8  10 1
            2    10   9 1
            3     3   4 2
            4     9  11 1 #Up
            5    10   4 1 #Down
            6    10   7 1
            7     4   5 1
            8     7  12 2
            9     5   6 2
            10    7  13 1
            11    6   1 1
            12   13  14 1
            13   13  15 1
            14   15  16 1
            15    1   2 2
            16   14  17 1
            17    2   3 1
            18   11  18 1
            19    8   9 1

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