| Entry |
|
|---|
| Name |
Mosapride (INN);
Mosart (TN) |
|---|
| Formula |
C21H25ClFN3O3
|
|---|
| Exact mass |
421.1568
|
|---|
| Mol weight |
421.8929
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Gastrointestinal agent
DG01763 Propulsive
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
| Product (DG01285): | D01994<JP> |
|
|---|
| Efficacy |
Prokinetic, Serotonin receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03F PROPULSIVES
A03FA Propulsives
A03FA09 Mosapride
D08236 Mosapride (INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01763 Propulsive
DG01285 Mosapride
D08236 Mosapride
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01285 Mosapride
D08236 Mosapride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR4
D08236 Mosapride (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08236
Drug groups [BR:br08330]
Gastrointestinal agent
DG01763 Propulsive
DG01285 Mosapride
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01285 Mosapride
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 29
1 C8y C 11.3400 -16.1700
2 C8y C 11.3400 -14.7700
3 C8x C 12.6000 -14.0700
4 C8y C 13.7900 -14.7700
5 C8y C 13.7900 -16.1700
6 C8x C 12.6000 -16.8700
7 C5a C 14.9800 -16.8700
8 N1b N 16.2400 -16.1700
9 C1b C 17.4300 -16.8700
10 C1y C 18.6200 -16.1700
11 O2x O 18.6200 -14.7700
12 C1x C 19.8800 -14.0700
13 C1x C 21.0700 -14.7700
14 N1y N 21.0700 -16.1700
15 C1x C 19.8800 -16.8700
16 O2a O 14.9800 -14.0700
17 C1b C 16.2400 -14.7700
18 C1a C 17.4300 -14.0700
19 X Cl 10.1500 -16.8700
20 N1a N 10.1500 -14.0700
21 O5a O 14.9800 -18.2700
22 C1b C 22.2600 -16.8700
23 C8y C 23.5200 -16.1700
24 C8x C 23.5200 -14.7700
25 C8x C 24.7100 -14.0700
26 C8y C 25.9000 -14.7700
27 C8x C 25.9000 -16.1700
28 C8x C 24.7100 -16.8700
29 X F 27.1600 -14.0700
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 10 15 1
17 4 16 1
18 16 17 1
19 17 18 1
20 1 19 1
21 2 20 1
22 7 21 2
23 14 22 1
24 22 23 1
25 23 24 2
26 24 25 1
27 25 26 2
28 26 27 1
29 27 28 2
30 23 28 1
31 26 29 1
|
|---|
