KEGG   DRUG: D08236Help
Entry
D08236                      Drug                                   

Name
Mosapride (INN);
Mosart (TN)
Formula
C21H25ClFN3O3
Exact mass
421.1568
Mol weight
421.8929
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Peristaltic stimulant
Target
5-HT4-receptor agonist [HSA:3360] [KO:K04160]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor [HSA:3360] [KO:K04160]
     Mosapride
      D08236  Mosapride (INN)
BRITE hierarchy
Other DBs
CAS: 
112885-41-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   C8y C    16.8700  -17.5700
            2   C8y C    16.8700  -18.9700
            3   C8x C    18.1300  -19.6700
            4   C8y C    19.3200  -18.9700
            5   C8y C    19.3200  -17.5700
            6   C8x C    18.1300  -16.8700
            7   C5a C    20.5100  -16.8700
            8   N1b N    21.7700  -17.5700
            9   C1b C    22.9600  -16.8700
            10  C1y C    24.1500  -17.5700
            11  O2x O    24.1500  -18.9700
            12  C1x C    25.4100  -19.6700
            13  C1x C    26.6000  -18.9700
            14  N1y N    26.6000  -17.5700
            15  C1x C    25.4100  -16.8700
            16  O2a O    20.5100  -19.6700
            17  C1b C    21.7700  -18.9700
            18  C1a C    22.9600  -19.6700
            19  X   Cl   15.6800  -16.8700
            20  N1a N    15.6800  -19.6700
            21  O5a O    20.5100  -15.4700
            22  C1b C    27.7900  -16.8700
            23  C8y C    29.0500  -17.5700
            24  C8x C    29.0500  -18.9700
            25  C8x C    30.2400  -19.6700
            26  C8y C    31.4300  -18.9700
            27  C8x C    31.4300  -17.5700
            28  C8x C    30.2400  -16.8700
            29  X   F    32.6900  -19.6700
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   10  15 1
            17    4  16 1
            18   16  17 1
            19   17  18 1
            20    1  19 1
            21    2  20 1
            22    7  21 2
            23   14  22 1
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   27  28 2
            30   23  28 1
            31   26  29 1

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