KEGG   DRUG: MoxifloxacinHelp
Entry
D08237                      Drug                                   

Name
Moxifloxacin (INN);
Avelox IV (TN)
Formula
C21H24FN3O4
Exact mass
401.1751
Mol weight
401.4314
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Structure map
Quinolones
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA14 Moxifloxacin
      D08237  Moxifloxacin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE07 Moxifloxacin
      D08237  Moxifloxacin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Moxifloxacin
    D08237  Moxifloxacin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Moxifloxacin
      D08237  Moxifloxacin (INN)
BRITE hierarchy
Other DBs
CAS: 
151096-09-2
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        29
            1   C8y C    20.3092  -16.2675
            2   N4y N    21.4964  -16.9658
            3   C8y C    19.1220  -16.9658
            4   C8y C    20.3092  -14.8708
            5   C1y C    21.4964  -18.3625
            6   C8x C    22.7534  -16.2675
            7   C8y C    17.8649  -16.2675
            8   O2a O    19.1220  -18.3625
            9   C8y C    21.4964  -14.1724
            10  C8x C    19.1220  -14.1724
            11  C1x C    22.1947  -19.5497
            12  C1x C    20.7980  -19.5497
            13  C8y C    22.7534  -14.8708
            14  N1y N    16.7476  -17.1753
            15  C8y C    17.8649  -14.8708
            16  C1a C    17.8649  -19.0609
            17  O5x O    21.4964  -12.7757
            18  C6a C    23.9406  -14.1724
            19  C1x C    15.9096  -16.0580
            20  C1x C    15.9096  -18.2927
            21  X   F    16.6777  -14.1724
            22  O6a O    25.1278  -14.8708
            23  O6a O    23.9406  -12.7757
            24  C1y C    14.5827  -16.4770
            25  C1y C    14.5827  -17.8737
            26  C1x C    13.3257  -15.7786
            27  N1x N    13.3955  -18.5720
            28  C1x C    12.1385  -16.4770
            29  C1x C    12.1385  -17.8737
BOND        33
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     4  10 2
            10    5  11 1
            11    5  12 1
            12    6  13 2
            13    7  14 1
            14    7  15 2
            15    8  16 1
            16    9  17 2
            17   13  18 1
            18   14  19 1
            19   14  20 1
            20   15  21 1
            21   18  22 1
            22   18  23 2
            23   19  24 1
            24   20  25 1
            25   24  26 1
            26   25  27 1
            27   26  28 1
            28   27  29 1
            29    9  13 1
            30   10  15 1
            31   11  12 1
            32   24  25 1
            33   28  29 1

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