KEGG   DRUG: D08244Help
Entry
D08244                      Drug                                   

Name
Naftidrofuryl (INN);
Drosunal (TN)
Formula
C24H33NO3
Exact mass
383.246
Mol weight
383.5237
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Vasodilator;
Peripheric
Remark
ATC code: 
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C04 PERIPHERAL VASODILATORS
   C04A PERIPHERAL VASODILATORS
    C04AX Other peripheral vasodilators
     C04AX21 Naftidrofuryl
      D08244  Naftidrofuryl (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor [HSA:3356] [KO:K04157]
     Naftidrofuryl [ATC:C04AX21]
      D08244  Naftidrofuryl (INN)
BRITE hierarchy
Other DBs
CAS: 
31329-57-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C8x C    17.5700  -20.2300
            2   C8x C    17.5700  -21.6300
            3   C8x C    18.8300  -22.3300
            4   C8y C    20.0200  -21.6300
            5   C8y C    20.0200  -20.2300
            6   C8x C    18.8300  -19.5300
            7   C8x C    21.2100  -22.3300
            8   C8x C    22.4700  -21.6300
            9   C8x C    22.4700  -20.2300
            10  C8y C    21.2100  -19.5300
            11  C1b C    21.2100  -18.1300
            12  C1c C    22.4700  -17.4300
            13  C7a C    23.6600  -18.1300
            14  C1b C    22.4700  -16.0300
            15  O7a O    24.8500  -17.4300
            16  O6a O    23.6600  -19.5300
            17  C1b C    26.0400  -18.1300
            18  C1b C    27.2300  -17.4300
            19  N1c N    28.4200  -18.1300
            20  C1b C    29.6100  -17.4300
            21  C1a C    30.8000  -18.1300
            22  C1b C    28.4200  -19.5300
            23  C1a C    29.6100  -20.2300
            24  C1y C    23.6600  -15.3300
            25  O2x O    23.6600  -13.9300
            26  C1x C    24.9900  -15.7500
            27  C1x C    25.8300  -14.6300
            28  C1x C    24.9900  -13.5100
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   12  14 1
            16   13  15 1
            17   13  16 2
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   19  22 1
            24   22  23 1
            25   14  24 1
            26   24  25 1
            27   24  26 1
            28   26  27 1
            29   27  28 1
            30   25  28 1

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