KEGG   DRUG: D08268Help
Entry
D08268                      Drug                                   

Name
Netilmicin (INN);
NTL;
Netira (TN)
Formula
C21H41N5O7
Exact mass
475.3006
Mol weight
475.5795
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibiotic, aminoglucosidase
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Semisynthetic aminoglycoside
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB07 Netilmicin
      D08268  Netilmicin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA23 Netilmicin
      D08268  Netilmicin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Aminoglycosides
     Netilmicin
      D08268  Netilmicin (INN)
BRITE hierarchy
Other DBs
CAS: 
56391-56-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        33
            1   C1y C    24.1500  -18.1300
            2   C1y C    25.3400  -18.8300
            3   C1y C    24.1500  -16.7300
            4   O2a O    22.8900  -18.8300
            5   C1x C    26.5300  -18.1300
            6   N1b N    25.3400  -20.2300
            7   C1y C    25.3400  -16.0300
            8   O1a O    22.8900  -16.0300
            9   C1y C    21.7000  -19.5300
            10  C1y C    26.5300  -16.7300
            11  C1b C    26.5300  -20.9300
            12  O2a O    25.3400  -14.6300
            13  C1y C    21.7000  -20.9300
            14  O2x O    20.5100  -18.8300
            15  N1a N    27.8600  -16.3800
            16  C1a C    26.6000  -22.3300
            17  C1y C    26.6000  -13.9300
            18  C1y C    20.5100  -21.6300
            19  O1a O    22.8900  -21.6300
            20  C1x C    19.2500  -19.5300
            21  O2x O    27.7900  -14.6300
            22  C1y C    26.6000  -12.5300
            23  C1z C    19.2500  -20.9300
            24  N1b N    20.5100  -23.0300
            25  C2y C    28.9800  -13.9300
            26  C1x C    27.7900  -11.8300
            27  N1a N    25.4100  -11.8300
            28  C1a C    19.5300  -24.0100
            29  C2x C    28.9800  -12.5300
            30  C1b C    30.2400  -14.6300
            31  N1a N    30.2400  -16.0300
            32  C1a C    18.0600  -21.6300
            33  O1a O    18.0600  -20.2300
BOND        35
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Up
            8     9   4 1 #Down
            9     5  10 1
            10    6  11 1
            11    7  12 1 #Down
            12    9  13 1
            13    9  14 1
            14   10  15 1 #Up
            15   11  16 1
            16   17  12 1 #Down
            17   13  18 1
            18   13  19 1 #Down
            19   14  20 1
            20   17  21 1
            21   17  22 1
            22   18  23 1
            23   18  24 1 #Up
            24   21  25 1
            25   22  26 1
            26   22  27 1 #Down
            27   24  28 1
            28   25  29 2
            29   25  30 1
            30   30  31 1
            31    7  10 1
            32   20  23 1
            33   26  29 1
            34   23  32 1
            35   23  33 1 #Up

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