KEGG   DRUG: D08283Help
Entry
D08283                      Drug                                   
Name
Nordazepam (INN);
Calmday (TN)
Formula
C15H11ClN2O
Exact mass
270.056
Mol weight
270.7136
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Tranquilizer
Remark
Same as: 
ATC code: 
Comment
Benzodiazepines
Target
GABAA-receptor (benzodiazepine binding site) agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Metabolism
Enzyme: CYP2C19 [HSA:1557], CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
Anxiolytics
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA16 Nordazepam
      D08283  Nordazepam (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site) [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05176 K05177 K05178 K05179 K05180 K05181 K05182 K05183 K05184 K05185 K05186 K05187 K05188 K05189 K05192]
     Nordazepam [ATC:N05BA16]
      D08283  Nordazepam (INN)
BRITE hierarchy
Other DBs
CAS: 
1088-11-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C2y C    25.6900  -16.7300
            2   C8y C    24.8500  -15.6100
            3   C8y C    25.2000  -14.2800
            4   N1x N    26.4600  -13.7200
            5   N2x N    27.0900  -16.7300
            6   C5x C    27.7200  -14.3500
            7   C1x C    28.0000  -15.6800
            8   C8x C    24.2200  -13.3000
            9   C8x C    22.8200  -13.7200
            10  C8y C    22.5400  -15.0500
            11  C8x C    23.5200  -16.0300
            12  O5x O    28.7700  -13.3700
            13  X   Cl   21.1400  -15.4700
            14  C8y C    25.0600  -17.9900
            15  C8x C    23.6600  -17.9900
            16  C8x C    22.9600  -19.2500
            17  C8x C    23.6600  -20.3700
            18  C8x C    25.0600  -20.3700
            19  C8x C    25.7600  -19.2500
BOND        21
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   14  19 2

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