KEGG   DRUG: NorfenefrineHelp
Entry
D08286                      Drug                                   

Name
Norfenefrine (INN)
Formula
C8H11NO2
Exact mass
153.079
Mol weight
153.1784
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
    DG01654  alpha1-Adrenergic receptor specific agonist
Remark
ATC code: 
Chemical group: 
Activity
alfa-Sympathomimetic
Target
alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Salivary secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA05 Norfenefrine
      D08286  Norfenefrine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Norfenefrine
      D08286  Norfenefrine (INN)
BRITE hierarchy
Other DBs
CAS: 
536-21-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        11
            1   C8y C    13.5100  -27.2300
            2   C8x C    13.5100  -28.6300
            3   C8x C    14.7224  -29.3300
            4   C8x C    15.9349  -28.6300
            5   C8y C    15.9349  -27.2300
            6   C8x C    14.7224  -26.5300
            7   C1c C    17.1660  -26.5190
            8   C1b C    18.3712  -27.2147
            9   O1a O    17.1657  -25.1301
            10  N1a N    19.5535  -26.5319
            11  O1a O    12.2976  -26.5300
BOND        11
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     7   9 1
            10    8  10 1
            11    1  11 1

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